| 党参的化学成分研究 |
| |
| 引用本文： | 冯亚静,王晓霞,庄鹏宇,张丹阳,高磊,陈金铭,韩刚.党参的化学成分研究[J].中国中药杂志,2017,42(1):135-139. |
| |
| 作者姓名： | 冯亚静 王晓霞 庄鹏宇 张丹阳 高磊 陈金铭 韩刚 |
| |
| 作者单位： | 华北理工大学 公共卫生学院, 河北 唐山 063000,华北理工大学 药学院, 河北 唐山 063000,华北理工大学 药学院, 河北 唐山 063000,华北理工大学 药学院, 河北 唐山 063000,华北理工大学 药学院, 河北 唐山 063000,华北理工大学 公共卫生学院, 河北 唐山 063000,华北理工大学 药学院, 河北 唐山 063000 |
| |
| 基金项目： | 国家重点基础研究发展计划（973）项目（2012CB518402） |
| |
| 摘 要： | 综合运用各种色谱分离技术对党参的水提取物进行化学成分研究,利用各种波谱技术确定化合物的结构。该研究从党参中分离得到8个单体成分,分别鉴定为:(-)-(7R,8S,7'E)-3',4-dihydroxy-3-methoxy-8,4'-oxyneoligna-7'-ene-7,9,9'-triol(1)、9-(tetrahydropyran-2-yl)-nona-trans,trans-2,8-diene-4,6-diyn-1-ol(2)、9-(tetrahydropyran-2-yl)-trans-non-8-ene-4,6-diyn-1-ol(3)、党参炔苷元(4)、党参炔苷(5)、去氢双松柏醇(6)、5-羟甲基-糠醛(7)、4,4'-dihydroxy-3,3'-dimethoxy-trans-stilbene(8)。其中,化合物1为新的木脂素类化合物,2,3为首次从党参属中分离得到。
|
| 关 键 词： | 党参 桔梗科 化学成分 新木脂素 |
| 收稿时间： | 2016/7/21 0:00:00 |
Study on chemical constituents of Codonopsis pilosula |
| |
| FENG Ya-jing,WANG Xiao-xi,ZHUANG Peng-yu,ZHANG Dan-yang,GAO Lei,CHEN Jin-ming and HAN Gang.Study on chemical constituents of Codonopsis pilosula[J].China Journal of Chinese Materia Medica,2017,42(1):135-139. |
| |
| Authors: | FENG Ya-jing WANG Xiao-xi ZHUANG Peng-yu ZHANG Dan-yang GAO Lei CHEN Jin-ming and HAN Gang |
| |
| Affiliation: | School of Public Health, North China University of Science and Technology, Tangshan 063000, China,College of Pharmacy, North China University of Science and Technology, Tangshan 063000, China,College of Pharmacy, North China University of Science and Technology, Tangshan 063000, China,College of Pharmacy, North China University of Science and Technology, Tangshan 063000, China,College of Pharmacy, North China University of Science and Technology, Tangshan 063000, China,School of Public Health, North China University of Science and Technology, Tangshan 063000, China and College of Pharmacy, North China University of Science and Technology, Tangshan 063000, China |
| |
| Abstract: | A new neolignan, (-)-(7R,8S,7''E)-3'',4-dihydroxy-3-methoxy-8,4''-oxyneoligna-7''-ene-7,9,9''-triol(1), and seven known compounds, 9-(tetrahydropyran-2-yl)-nona-trans,trans-2,8-diene-4,6-diyn-1-ol (2), 9-(tetrahydropyran-2-yl)-trans-non-8-ene-4,6-diyn-1-ol (3), lobetyol (4), lobetyolin (5),dehydrodieoniferyl alcohol (6), 5-hydroxymethylfurfural (7), and 4, 4''-dihydroxy-3, 3''-dimethoxy-trans-stilbene (8), were isolated from the H2O extract of Codonopsis pilosula. The structures of 1-8 were elucidated by spectroscopic methods including NMR, HR-ESI-MS, and CD. In addition, compounds 2 and 3 were isolated from the genus Codonopsis for the first time. |
| |
| Keywords: | Codonopsis pilosula Campanulaceae chemical constituent neolignan |
| 本文献已被 CNKI 等数据库收录！ |
|
