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新生鼠垂体移植抗衰老作用的实验研究
引用本文:赵放理,梅俊.新生鼠垂体移植抗衰老作用的实验研究[J].中国老年学杂志,1993(2).
作者姓名:赵放理  梅俊
作者单位:西安医科大学脑和神经研究室,西安医科大学脑和神经研究室 西安 710061,西安 710061
摘    要:为探讨垂体移植有无抗衰老作用,我们在老龄SD大鼠第Ⅲ脑室内移植新生鼠垂体。结果发现,移植组老龄鼠体重降低速度减慢,体温趋于相对恒定,运动平衡能力改善,雌鼠性功能衰退进程延缓,平均及最大活存期明显延长,萎缩的性腺有一定程度的代偿。提示新生鼠垂体移植于老年宿主后似有一定的抗衰老作用。

关 键 词:垂体移植  神经内分泌系统  衰老  抗衰老  阴道涂片

Studies of the Effect on the Anti-Ageing Process in Rats with Neonatal Pituitary Transplanting
Zhao FangLi,Mei Jun.Studies of the Effect on the Anti-Ageing Process in Rats with Neonatal Pituitary Transplanting[J].Chinese Journal of Gerontology,1993(2).
Authors:Zhao FangLi  Mei Jun
Affiliation:Zhao FangLi,Mei Jun Department of Brain and Nerve,Xi'an Medical University,Xi'an 710061
Abstract:In order to exploer whether pituitary transplantation has some anti-ageing action, We implanted a neonatalpituitary tissue of rats into the third venticle of aged Sprague-Dawley rats. The results showed that compareingwith the control group of old rats, the rate of body weights loss of implanted aged rats was discreased, the bodytemperature was tended constant, the ability to maintain balance on a narrow wooden bridge was immproved,failure of reproductive function in female group was delayed, the average lifespan and maximum lifespan wereprolonged significantly, and the atrophic ovaries and testes have got a recovery to a certain degree. All these re-sults suggest that the neonatal pituitary transplantation seems to have some anti-ageing action on old rats.
Keywords:Pituitary Transplantation  Neuroendocrine System  Ageing  Anti-Ageing  Vaginal Smear
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