| 明胶海绵吸附凝血酶对脑水肿影响的实验研究 |
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| 引用本文： | 李泽福,李建民,赵学林,李勐,徐军,刘永良.明胶海绵吸附凝血酶对脑水肿影响的实验研究[J].滨州医学院学报,2003,26(2):89-90. |
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| 作者姓名： | 李泽福 李建民 赵学林 李勐 徐军 刘永良 |
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| 作者单位： | 滨州医学院附属医院神经外科,滨州市,256603 |
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| 摘 要： | 目的：观察手术应用明胶海绵吸附凝血酶对脑水肿的影响。方法：将大鼠皮层切除明胶海绵吸附凝血酶置入受损处。24h后取脑，干-湿重法测定脑组织的含水量，结果：在同侧基底节，明胶海绵吸附上凝血酶引起明显脑水肿。水蛭素能减轻脑水肿。结论：手术应用明胶海绵吸附凝血酶止血可导致脑水肿形成。
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| 关 键 词： | 明胶海绵 吸附 凝血酶 脑水肿 实验研究 |
| 文章编号： | 1001-9510(2003)02-0089-02 |
| 修稿时间： | 2002年12月5日 |
THE EFFECT OF THROMBIN-SOAKED GELATIN SPONGE ON RAT BRAIN EDEMA |
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| Li Zefu,Li Jianmin,Zhao Xuelin,et al.THE EFFECT OF THROMBIN-SOAKED GELATIN SPONGE ON RAT BRAIN EDEMA[J].Journal of Binzhou Medical College,2003,26(2):89-90. |
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| Authors: | Li Zefu Li Jianmin Zhao Xuelin |
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| Abstract: | Objective:To study the effect of thrombin soaked gelatin sponge on brain edema.Methods:In the model,frontal cortex was excised (3 mm 3)?Gelation sponge was soaked with saline and thrombin or thrombin added hirudin and placed in the lesion site.Brain edema was determined by wet/dry weight 24 hours after exposure.Results:Thrombin soaked gelatin sponges caused significant brain edema in the right basal ganglia.Hirudin prevented thrombin induced edema.Conclusion:Thrombin soaked gelation sponges can cause or enhance significant brain edema in rats. |
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| Keywords: | thrombin gelatin sponge brain edema |
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