气相色谱-串联质谱（GC-MS/MS）的应用研究进展

气相色谱-串联质谱（GC-MS/MS）依靠其高灵敏度和强抗干扰能力，在化学、生物和环境分析中已得到广泛的应用。通过文献调研确认了国内外GC-MS/MS应用研究最多的几个方向，简述了自2000年以来GC-MS/MS在农药残留、环境污染物（主要是多环芳烃、多氯联苯、多溴联苯醚和二噁英等）和类固醇激素等检测方面的应用。并对比分析了不同目标物，GC-MS/MS相对于其他仪器的优势以及应用于不同目标物时常用的前处理方法。对国内GC-MS/MS应用的基本方向进行了综述，并展望了其发展及应用前景。

Research Progress on Application of GC-MS/MS

Relying on its high sensitivity and strong anti-jamming capability, gas chromatography-tandem mass spectrometry(GC-MS/MS) was widely used in chemical, biological and environmental analysis. This paper overviewed recent progress on the application of GC-MS/MS since 2000. Most of the relevant works were in the area of pesticide residues, environmental pollutants (including PAHs, PCBs, PBDEs, PCDD/Fs) and steroid hormones. The discussion mainly contained two aspects. First, the advantages of GC-MS/MS in the analysis of different targets were compared to other instruments. Second, the methods of sample treatment were widely used and suitable for GC-MS/MS analysis. Furthermore, domestic application of GC-MS/MS was stated simply，and the future development of application in GC-MS/MS was reviewed.