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Reversible ischemia determined by xenon-enhanced CT after 90 minutes of complete basilar artery occlusion
Authors:EI Levy  AM Scarrow  E Kanal  G Rubin  H Yonas  L Kirby
Affiliation:Department of Neurological Surgery, Presbyterian University Hospital, The University of Pittsburgh Medical Center, PA 15213, USA.
Abstract:Intraarterial thrombolytic therapy decreases mortality in the treatment of acute basilar artery occlusion. An acute decrease in cerebral blood flow (CBF) (<12 mL/100 g per minute) has been reported to invariably result in infarction. We report a case of acute basilar artery occlusion, recanalized within 90 minutes, with reversal of CBF of less than 6 mL/100 g per minute. After reperfusion, areas with persistent CBF of 6 mL/100 g per minute resulted in infarctions on subsequent CT studies. Parenchymal viability is possible after 90 minutes of posterior CBF of 6 mL/100 g per minute.
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