我院Ⅰ类切口手术预防性应用抗菌药物干预前后对比分析

目的:调研干预前后我院Ⅰ类切口手术围手术期预防性应用抗菌药物的状况,为临床合理用药提供参考。方法:根据国家开展的抗菌药物专项整治活动精神及医院抗菌药物管理要求,抽取我院2011年1-6月(干预前)和2012年1-6月(干预后)Ⅰ类切口手术出院病历各180份,对比分析干预前后抗菌药物的使用情况。结果:与2011年相比,2012年1-6月我院Ⅰ类切口手术预防性应用抗菌药物使用率由98.33%降至46.11%,联合用药比例由22.60%降至2.41%,品种选择合理率由29.38%升至67.47%,用药时机合理率由16.38%升至61.45%,用药疗程合理率由8.47%升至53.01%。结论:我院采取的干预措施提高了Ⅰ类切口手术围手术期预防用药的合理性,但仍存在预防性抗菌药物使用率偏高、预防用药时间偏长等不合理之处,需进一步加强监督管理力度,促进围手术期抗菌药物的合理使用。

Comparative study on the application of prophylactic antibacterial agents in type I incision operation before and after intervention

Objective： To compare and analyze the usage of prophylactic antibacterial drugs during perioperative period in type I incision operations before and after intervention,and provide references for rational use of antibacterial drugs in clinic.Methods： According to the content of the national renovation of the antibacterial agents and the requirement of our hospital,a comparative study of the usage of antibacterial drugs was conducted on the 180 cases of type I incision operations collected from January to June of 2011（pre-intervention） and 180 others from January to June of 2012（post-intervention）.Results： Compared with pre-intervention in 2011,the percentage of prophylactic use of antibacterials decreased from 98.33% to 46.11% after intervention in 2012;the rate of combination use of drugs decreased from 22.60% to 2.41%;the rate of reasonable choice of antibacterials increased from 29.38% to 67.47%;the rate of rationality of administration time and medication duration increased from 16.38% to 61.45% and from 8.47% to 53.01%,respectively.Conclusion： The intervention measures were proved to be practicable and effective in improving the rationality of prophylactic use of antibacterial drugs during perioperative period in type I incision operations.Still there were some irrational problems,such as high rate of prophylactic use of antibacterial drugs and long duration time for preventing infection.Therefore,we should strengthen the management to promote the rational use of antibacterial drugs during perioperative period.