A critical review of bioceramics for magnetic hyperthermia |
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| Authors: | Omid Sedighi Amirhossein Alaghmandfard Maziar Montazerian Francesco Baino |
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| Affiliation: | 1. Department of Materials Science and Engineering, Sharif University of Technology, Tehran, Iran;2. Northeastern Laboratory of Evaluation and Development of Biomaterials, Academic Unit of Materials Engineering, Federal University of Campina Grande, Campina Grande, Brazil;3. Institute of Materials Physics and Engineering, Department of Applied Science and Technology, Politecnico di Torino, Torino, Italy |
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| Abstract: | Magnetic hyperthermia (HT) using biocompatible ceramics is a ground-breaking, competent, and safe thermo-therapeutic strategy for cancer treatment. The magnetic properties of bioceramics, along with their structure and synthesis parameters, are responsible for the controlled heating of malignant tumors and are the key to clinical success. After providing a brief overview of magnetism and its significance in biomedicine, this review deals with materials selection and synthesis methods of bioceramics/glasses used for HT. Relevant research carried out on promising bioceramics for magnetic HT, with a focus on their size, shape, surface functionalization, magnetic field parameters, and in vitro/in vivo properties to optimize cancer therapy, is also discussed. Recent progress in magnetic HT combined with chemotherapy and phototherapy is especially highlighted, with the aim to provide interdisciplinary knowledge to advance further the applications of bioceramics in this field. |
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| Keywords: | bioceramics cancer glass magnetic materials nanomaterials properties |
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