| Effects of interleukin-1α on platelet-derived growth factor release from bovine cerebral microvascular endothelial cells |
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| 引用本文： | 李坚,张珉,芮耀诚.Effects of interleukin-1α on platelet-derived growth factor release from bovine cerebral microvascular endothelial cells[J].中国人民解放军军医大学学报,1997(1). |
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| 作者姓名： | 李坚 张珉 芮耀诚 |
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| 作者单位： | Department of Pharmacology，Faculty of Pharmacy，Second Military Medical University，Shanghai，200433 |
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| 摘 要： | ThepreviousworkofourlabshowedthatILlastimulatedtheproliferationofbovinecerebralmicrovascularsmoothmusclecells(BCMSMC);",butthemechanismremainsunknown.EarlierreportsshowedthatIL--1stimulatedendothelialcellstosecretesomefactorswhichweremitogenictothevascularsmoothmusclecells2].Amongthosefactors,platelet--derivedgrowthfactor(PDGF)wasthemainone3j.OurexperimentwasdesignedtoinvestigatetheeffectofPDGFonproliferationofbovinecerebralmicrovascularsmoothmusclecells(BCMSMC)stimulatedbyIL--la.…
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