| 玫瑰活心胶囊的质量标准研究 |
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| 引用本文： | 闫雪生,刘昭强,姚乾元,付征.玫瑰活心胶囊的质量标准研究[J].中国实用医药,2009,4(23):3-4. |
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| 作者姓名： | 闫雪生 刘昭强 姚乾元 付征 |
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| 作者单位： | 1. 山东省中医药研究院,250014
2. 山东中医药大学,03级中药学四班 |
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| 摘 要： | 目的建立玫瑰活心胶囊的质量标准。方法采用薄层色谱法对玫瑰花进行了定性鉴别，采用高效液相色谱法测定了胶囊中没食子酸的含量，采用Lichrospher C18柱（5um，200mm×4．6mm）；检测波长273；流动相：甲醇-水-磷酸（5：95：0．4）；流速：1．0ml／min；柱温：30℃。结果此法线性范围8．51—272．4ug/ml，r=0．9997；没食子酸的平均回收率为101．12％（RSD=2．09％，n=5）。结论该方法稳定、可靠，可作为该制剂的质量控制方法。
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| 关 键 词： | 玫瑰活心胶囊 质量标准 薄层色谱 高效液相色谱 |
The Study on the Quality Standard for Meigui Huoxin Capsule |
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| Affiliation: | YAN Xue-sheng , LIU Zhao-qiang , YAO Qian-yuan , et al.(Shandong Academy of TCM ; Jinan ; Shandong 250014, China) |
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| Abstract: | Objective To develop a quality standard for Meigui Huoxin Scapsule. Methods TLC was used to identify the ingredient of Flos Rosae Rugosae. Meanwhile, the content of gallic acid in Meigui Huoxin capsule was determined by HPLC with Lichrospher C18 column（5 um,200 mm×4.6 mm）. The detection wavelength was 273 nm; methanol-water- H3PO4 solution（5：95：0.4） was used as mobile phase,the rate of 1.0ml/ minand the colum temperature was at 30℃. Results The method was linear with in the range of 8.51-272. 4？ g/ml（ r = 0. 9997 ）. The average recovery of gallic acid was 101.12% , （ RSD = 2. 09% , n = 5 ）. Conclusion The method is accurate, reliable, and can be used for quality control of the production. |
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| Keywords: | Meigui Huoxin capsule Quality standard TLc HPLC |
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