聪灵胶囊对小鼠软脑膜微循环障碍的改善作用

目的 观察聪灵胶囊对小鼠软脑膜微循环障碍的改善作用。方法 将60只小鼠随机分为聪灵胶囊大、中、小剂量组、阳性对照组和正常对照组，分别于灌胃给药10d后，开颅窗观察小鼠软脑膜微循环，然后在软脑膜局部滴加去甲肾上腺素复制微循环障碍模型，观察微循环障碍时小鼠软脑膜微循环。结果 聪灵胶囊各剂量组均可改善去甲肾上腺素所致的小鼠软脑膜局部微循环障碍．使微动脉扩张，血流增快，每视野交织网点数增多，对血流流态也有一定的改善作用，使血色变红。9min后聪灵胶囊各剂量组软脑膜局部微循环障碍基本恢复，而空白对照组恢复不明显。结论 聪灵胶囊能改善小鼠软脑膜微循环。

Effect of Congling Capsule on Mice Cerebral Pial Microcirculation

Objective To observe the effect of Congling Capsule(CLC)on mice cerebral pial microcirculation.Methods The effect of CLC on mice cerebral pial microcirculation was observed under normal state and microcirculation disturbance state was established by means of dripping noradrenaline on the cerebral pial.Results CLC dilated peripheral artery of cerebral pial microcirculation and increased capillary network point number and accelerated the rate of blood flow of microcirculation.Besides,the blood is redder.Conclusion CLC can improve mice cerebral pial microcirculation.