核桃楸的化学成分研究进展

核桃楸具有很好的药用价值,其树皮、叶和果实多可入药。系统查阅近20年国内外有关核桃楸的研究报道,对核桃楸的化学成分、生物活性进行了综述。目前为止,从核桃楸中分离得到的化学成分主要有黄酮类、醌衍生物、酚类、萜类和挥发油等。药理学研究表明,无论是核桃楸粗提物还是其中所包含的具体的化学成分都表现出较好的消炎、止痛、抗肿瘤、抗氧化和抗病毒等生物活性。目前对核桃楸的化学成分和药理作用方面取得了一定的进展,但是缺少对其有效成分作用机制的深入研究。所以,对核桃楸的化学成分和作用机制进一步研究将有利于开发新的药物和充分利用天然药物资源。

Chemical Constituents of Juglans mandshurica

Juglans mandshurica has a high medical value, because its barks, leaves and fruits can be used as medicines. In this study, chemical components of J. mandshurica and bioactivities were reviewed based on the domestic and foreign literatures in the past 20 years. So far, flavones, quinines, polyphenols, terpenoids, volatile oils and other chemical constituents have been isolated from J. mandshurica. According to pharmacological studies, both its crude extracts and specific chemical constituents show good bioactivities, including anti-inflammatory, analgesic, anti-tumor, antioxidant and antiviral effects. Currently, despite some advances in its chemical constituents and pharmacological activities of J. mandshurica, there is still no intensive study on the action mechanism of its effective constituents. Therefore, further studies will be conducive to developing new medicines and making the most use of natural medical resources.