| DNA含量与嗜铬细胞瘤预后（附10例报告） |
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| 引用本文： | 颜醒愚,吴春林.DNA含量与嗜铬细胞瘤预后（附10例报告）[J].中华外科杂志,1997,35(3):176-177. |
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| 作者姓名： | 颜醒愚 吴春林 |
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| 作者单位： | 福建医学院附属第二医院泌尿外科，泉州市第一医院泌尿科 |
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| 摘 要： | 为研究ＤＮＡ倍体状况与嗜铬细胞瘤预后的关系，作者取６例肾上腺及４例肾上腺外嗜铬细胞瘤石蜡块标本，按照Ｈｅｄｌｅｙ′ｓ方法进行流式细胞计检查，测定ＤＮＡ倍体状况。回顾本组病例的临床及病理特点，并做随访。分析ＤＮＡ含量与预后的关系。结果显示：流式细胞计检查结果：异倍体７例、二倍体２例、四倍体１例。临床及病理诊断为恶性者为四倍体肿瘤。其它病例呈良性过程。作者认为，ＤＮＡ含量测定对嗜铬细胞瘤预后的判断有一定的价值。
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| 关 键 词： | 嗜铬细胞瘤 流式细胞术 DNA 预后 |
DNA content correlation with the prognosis of pheochromocytoma:10 cases report |
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| Yan Xingyu,Wu Chunlin,Wu Bocong,et al..DNA content correlation with the prognosis of pheochromocytoma:10 cases report[J].Chinese Journal of Surgery,1997,35(3):176-177. |
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| Authors: | Yan Xingyu Wu Chunlin Wu Bocong |
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| Affiliation: | Department of Urology, Second Affiliated Hospital, Fujian Medical College, Quanzhou. |
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| Abstract: | We investigated the relationship between DNA ploidy and the prognosis of pheochromocytoma. DNA ploidy studies on paraffin-embedded archival specimens from ten cases of pheochromocytoma were performed by flow cytometry according to Hedley's method. Clinical features and pathological results were investigated and follow-up was made. The values of DNA content in assessment of the prognosis of the tumor were discussed. Flow cytometry examination showed that seven cases had aneuploid, two deploid and one tetraploid. The malignent case was tetraploid, and died from matastasis to the bone. The other cases had a benign process. The examination of DNA content is of value in the assessment of the prognosis of pheochromocytoma. |
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| Keywords: | Pheochromocytoma Flow cytometry DNA Prognosis |
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