妥布霉素/地塞米松治疗白内障人工晶体术后迟发性前葡萄膜炎的疗效观察

目的:观察妥布霉素/地塞米松局部滴眼治疗白内障人工晶体植入术后迟发性前葡萄膜炎的疗效。方法:观察组19例(19只眼)给予妥布霉素/地塞米松滴眼液和眼膏治疗;对照组11例(11只眼)给予地塞米松10～20mg静脉滴注,3～5d后改为强的松顿服逐渐减量。2组同时以复方托吡卡胺滴眼液散瞳。结果:所有病例用药后3～5d炎症迅速控制,视力明显好转。观察组在治疗期间未发现不良反应;对照组部分病例出现激动、失眠,血压、血糖异常升高。结论:妥布霉素/地塞米松局部滴眼能有效治疗白内障术后迟发性前葡萄膜炎。

Efficacy of Tobradex in the Treatment of Delayed Anterior Uveitis Following Intraocular Lens Implantation for Patients with Cataract

OBJECTIVE： To investigate the clinical efficacy of tobradex in treating delayed anterior uveitis following intraocular lens implantation for patients with cataract. METHODS： 19 cases （19 eyes, observation group） were treated with tobradex gutta and tobradex eye ointment, while 11 （11 eyes） in control group were treated initially with dexamethasone by iv gtt, followed by prednisone taken at a draught with dosage decreased gradually after 3-5 days plus tropicamide eye drops for mydriasis. RESULTS： After treatment for 3 to 5 days, all patients achieved rapid improvement in inflammation and a favorable turn in visual acuity. No adverse reactions were noted in the observation group during treatment; however, the side effects such as irritation, insomnia, abnormal elevation in blood pressure and serum glucose level were noted in a few cases in the control group. CONCLUSION： Tobradex is effective for treating delayed anterior uveitis after cataract surgery.