| 智能纳米材料在细胞水平治疗疾病时的应用 |
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| 引用本文： | 彭坤,甘晓玲,段巧玲,罗晶,陈玉.智能纳米材料在细胞水平治疗疾病时的应用[J].中国神经再生研究,2009,13(29):5763-5766. |
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| 作者姓名： | 彭坤 甘晓玲 段巧玲 罗晶 陈玉 |
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| 作者单位： | 重庆医药高等专科学校,重庆医药高等专科学校,重庆医药高等专科学校,重庆医药高等专科学校,重庆医药高等专科学校 |
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| 摘 要： | 摘要：恶性肿瘤的常规治疗方法在临床应用中存在着或多或少的缺陷。为了实现靶向治疗及提高药物利用度等目的，一类具有智能效应(如热敏感、pH敏感、磁敏感以及光敏感等)的纳米材料已被应用到细胞水平治疗疾病的领域中。它们是通过药物靶向缓释、热效应和可控机械力等方式，杀死靶组织内的病理细胞，进而实现疾病的治愈。文章综合讨论了应用该类材料在细胞水平治疗疾病的最新进展，同时展望了其存在的问题以及发展前景。
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| 关 键 词： | 智能效应 纳米材料 细胞水平治疗疾病 |
Application of intelligent nanoparticles in treating diseases at the cellular level |
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| Peng Kun,Gan Xiao-ling,Duan Qiao-ling,Luo Jing and Chen Yu.Application of intelligent nanoparticles in treating diseases at the cellular level[J].Neural Regeneration Research,2009,13(29):5763-5766. |
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| Authors: | Peng Kun Gan Xiao-ling Duan Qiao-ling Luo Jing and Chen Yu |
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| Affiliation: | Department of Medical Technology, Chongqing Medical and Phamaceutical College, Chongqing 400030, China,Department of Medical Technology, Chongqing Medical and Phamaceutical College, Chongqing 400030, China,Department of Medical Technology, Chongqing Medical and Phamaceutical College, Chongqing 400030, China,Department of Medical Technology, Chongqing Medical and Phamaceutical College, Chongqing 400030, China,Department of Medical Technology, Chongqing Medical and Phamaceutical College, Chongqing 400030, China |
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| Abstract: | Conventional therapies for malignant tumors have some disadvantages in clinical application. To achieve targeted therapy and to improve the utilization degree of medicine, a kind of intelligent nanoparticles which possesses the characteristics of thermal response, pH sensitive, magnetic sensitive and light sensitive, are used in treating diseases at cellular level, killing pathological cells of targeted tissue with drugs targeted control release, thermal effect and control mechanical power. The latest development of the intelligent nanoparticles used in treating disease at cellular level and related issues were presented in the paper. |
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| Keywords: | Smart effect Nanoparticles Treating diseases at cellular level |
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