不同氨基酸螯合锌对小鼠抗氧化能力的影响

研究了三种形式锌源对小鼠抗氧化能力的影响。选用断奶小鼠(KM种)81只,随机分为三组(硫酸锌组、蛋氨酸锌组和亮氨酸锌组)。实验第一周,饲喂缺锌日粮。实验第8d起,三组饲喂加锌日粮。三种锌源均能提高肝脏、血清锌含量。补锌能使血清MDA含量明显下降,不同锌源间差异不显著(p>0.05)。补锌7d后,三种锌源提高了小鼠总抗氧化能力、总SOD、铜锌超氧化物歧化酶活性、谷胱甘肽含量,蛋氨锌组和亮氨酸锌组优于硫酸锌组酸(p<0.05)。亮氨酸锌,蛋氨酸锌的抗氧化能力优于硫酸锌,氨基酸螯合锌组之间抗氧化能力的差异不大。

Effects of Different Amino Acids Chelated Zinc on Antioxidation Ability of Mice

To investigate the effects of three forms of zinc sources on the antioxidation ability of weaning mice. Eighty-one weaning mice (KM) were allotted at random into 3 groups. In the first week, the mice were fed on the basal diet lack of zinc. Then the mice of group 1 were fed with zinc in zinc sulfate(ZnSO4), group 2 and 3 were supplemented respectively, with zinc in zinc- leucine (Zn-Leu) and zinc-methionine (Zn-Met). The serum and liver zinc contents were increased for the supply of three forms of zinc. The MDA (malondialdehyde) concentration was decreased when mice were supplemented with zinc but showed no significant difference for three different zinc sources(p>0.05). After 7 days of supplement with zinc, T-AOC,T-SOD, CuZn- SOD and GSH were all increased by zinc supplementation. There was difference between group 2,3 and group 1(p<0.05). Zn- Leu and Zn-Met improve the capability of antioxidtion more effectively than ZnSO4, but there is no significant difference in the capability of antioxidtion between the zinc chelated amino acid groups themselves.