厄贝沙坦与苯磺酸氨氯地平治疗轻中度原发性高血压的疗效比较

目的:比较厄贝沙坦(安博维)与苯磺酸氨氯地平(络活喜)治疗轻中度原发性高血压的降压疗效.方法:将2008年1月至2009年12月于明确诊断为轻中度原发性高血压患者100例随机分为安博维组和络活喜组各50例,分别应用安博维和络活喜治疗,比较两组治疗8周时的降压疗效.结果:治疗2周、4周、6周和8周时安博维组和络活喜组的降压有效(率)分别为35例(70%)、38例(76%)、41例(82%)、43例(86%)和36例(72%)、39例(78%)、40例(80%)、42例(84%),两组各疗程均无显著性差异.结论:厄贝沙坦(安博维)与苯磺酸氨氯地平(络活喜)治疗轻中度原发性高血压均可获良好疗效,且无明显不良反应.

Comparing of Antihypertensive Effect between Irbesartan and Amlodipine Besylate on Patients with Mild to Moderate Primary Hypertension

Objective： To compare the antlhypertensive effect between irbesartan and amlodipine besylate on patients with mild to moderate primary hypertension.Methods： 100 patients with mild to moderate primary hypertension from Jan 2008 to Dec 2009 were divided into irbesartan group and amlodipine group, each group was 50 cases and treated by irbesartan and amlodipine besylate respectively. The antihypertensive efficacy between the two groups was compared after 8 weeks of treatment. Results： The effective cases （rate） in irbesartan group and amlodipine group after 2 weeks, 4 weeks, 6 weeks and 8 weeks of treatment were 35 eases（70%）, 58 cases （76%） , 41 cases （82%）, 43 cases（86%） and 36 cases（72%）, 39 cases（78%）, 40 cases（80%）, 42cases （84%） respectively. The effects in each time were no significant difference. Conclusion： The antihypertensive effects between irbesartan and amlodipine besylate on patients with mild to moderate primary hypertension are good and no obvious side effects.