蔗糖铁注射液致急性喉头水肿

1例37岁女性患者因异位妊娠伴轻度贫血给予蔗糖铁注射液200 mg(10 ml)入0.9%氯化钠注射液250 ml静脉滴注。输注药液约3 min时,患者突然出现喉部不适、呕吐、刺激性呛咳,迅即出现呼吸困难、面色发绀,血氧饱和度0.87,血压87/56 mmHg(1 mmHg=0.133 kPa),心率121次/min,考虑为蔗糖铁注射液引起的喉头水肿。立即停止滴注,给予氧气吸入,先后静脉给予地塞米松共20 mg,患者症状逐渐好转。2 h后患者生命体征平稳,症状消失。

Acute laryngeal edema caused by iron sucrose injection

A 37-year-old female patient reeived an IV infusion of iron sucrose injection 200 mg dissolved in 250ml of 0.9%sodium chloride injection for ectopie pregnancy and mild anemia.About 3 minutes of infusion,the patient suddenly developed laryngeal discomfort and rritating cough.Her symptoms worsened rapidly,dyspnea and cyanosis appeared,oxygen saturation decreased to 0.87,blood pressure was 87/56 mmHg,and heart rate was 121 beats/min.Laryngeal edema induced by iron sucrose injection was considered.lron sucrose was discontinued immediately,oxygen inhalation and a total dose of dexamethasone 20 mg by IV infusion or IV injection were given.The patient's symptomns gradually improved.Two hours later,her vital signs were stable and the symptoms disappeared.