膀胱癌能量多普勒血流与肿瘤浸润深度的相关性研究

目的：用能量多普勒超声技术检测膀胱癌的血流情况，与病理结果对比，评价能量多普勒超声诊断膀胱癌的临床价值。材料和方法：对60例膀胱癌患者进行能量多普勒超声检查，观察肿瘤内血流分布情况，进行血流分级，测量PSV、EDV、RI值；对术后肿瘤进行HE染色确定浸润深度。结果：能量多普勒超声显示的肿瘤内血流分级、与肿瘤浸润深度、邻近器官浸润在P=0．05水平上相关显著，相关系数r分别为0.318、0．355；RI值与肿瘤浸润深度在P=0．01水平上相关显著，相关系数r为0．540。RI值与邻近器官浸润在P=0．05水平上相关显著，相关系数r=0．282。随着肿瘤浸润深度加深，邻近器官浸润趋势增加，血流信号显示增多、RI值增高。PSV、EDV与肿瘤浸润深度无明显相关性。结论：膀胱癌内彩色血流愈丰富，肿瘤浸润深度愈深，浸润邻近器官深度愈增加，RI值也随之增高，表明RI值对膀胱癌的定性诊断有一定价值。

Relationship of power Doppler flow on bladder cancer and depth of tumor invasion

Objective： To study the blood signal of bladder tumor in power Doppler technique and evaluate the clinical value of power Doppler image （PDI） in examining bladder cancer. Materials and Methods： All 60 patients were examined by ATL-HDI 5000 US system. Then the blood flow characteristics of bladder cancer and the blood flow grades were determined. Some data, such as PSV, EDV, RI, were got from it. The post-operation samples were dyed in HE to confirm the depth of invasion. Results： There were good relationship between PDI blood flow grade, depth of muscle layer invasion, and adjacent tissue invasion, P=0.05. Correlation coefficient was 0.318, 0.355 respectively. RI had significant correlation with depth of muscular layer invasion, P=0.01, and correlative coefficient was 0.540. RI correlated well with adjacent tissue invasion, P=0.05, the correlation coefficient was 0.282. As the depth of muscular layer and adjacent tissue invasion increased, the blood flow signals within tumor increased, RI was rising too. PSV, EDV had no correlation with depth of muscular layer invasion. Con- clusion： The more blood signals within tumors, the more tendency of invasion to muscle and adjacent tissue. RI is rising too, which shows RI has some values in determing the nature of bladder cancer.