息肉状脉络膜血管病变的诊治现状与进展

息肉状脉络膜血管病变(polypoidal choroidal vasculopathy,PCV)是一组常见的视网膜疾病,有色人种多见,在我国主要患者群以60岁左右为主,且女性较多见,该病目前发病原因不明且尚无特效药,眼底镜下可见橘红色病灶、出血及渗出,结合吲哚菁绿血管造影(indocyanine green angiography,ICGA)可做出诊断,近几年对其治疗的主要手段有光动力疗法(photodynamic therapy,PDT)、玻璃体腔抗VEGF药物注射疗法、针对并发症的手术治疗及其联合治疗,本文将对息肉状脉络膜血管病变的诊疗展开综述,对其未来的研究方向进行展望.

Status and progress of diagnosis and treatment of polypoidal choroidal vasculopathy

Polypoidal choroidal vasculopathy(PCV)is a common disease of the retina, the disease is more found in colored race. In China, the mainly nosogenic population is the female about 60 years old. The pathogenesis of PCV is unknown and there is no specific medicine at present. The funduscopic present is orangered lesions, bleed and exudation. Indocyanine green angiography(ICGA)could make a definite diagnosis of PCV. In recent, the main treatment of PCV includes photodynamic therapy, intravitreal anti-VEGF therapy, surgery for treatment of complications and combined therapy. We review the treatment and diagnosis of PCV, and propose the further research direction.