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红花注射液细菌内毒素检查可行性探讨
引用本文:侯永春,王晓蕾.红花注射液细菌内毒素检查可行性探讨[J].中国医院用药评价与分析,2008,8(4):282-283.
作者姓名:侯永春  王晓蕾
作者单位:中国人民解放军总医院药品供应中心,北京市,100853
摘    要:目的:建立红花注射液静滴用药时细菌内毒素的检查方法、方法:采用2个厂家的鲎试剂对红花注射液进行干扰试验。结果:鲎试剂浓度在0.25EU·mL^-1时,红花注射液经10倍稀释对细菌内毒素测定无干扰。结论:鲎法检测红花注射液静滴用药时的细菌内毒素可行。

关 键 词:细菌内毒素  鲎试剂  红花注射液

Feasibility of Bacterial Endotoxins Test for Honghua Injection
HOU Yong-chun,WANG Xiao-lei.Feasibility of Bacterial Endotoxins Test for Honghua Injection[J].Evaluation and Analysis of Drug-Use in Hospital of China,2008,8(4):282-283.
Authors:HOU Yong-chun  WANG Xiao-lei
Affiliation:(Drug Supply Center, PLA General Hospital, Beijing 100853, China)
Abstract:OBJECTIVE: To establish a method for bacterial endotoxins test for Honghua injection for intravenous drip. METHDOS: The interference test was conducted on Honghua injection using the tachypleus amebocyte lysate (TAL) from two manufacturers. RESULTS: No interference was noted for the bacterial endotoxin test when the TAL concentration was 0.25EU·ml^-1 and the Honghua injection was diluted to 10 times. CONCLUSION: It is feasible to use TAL for the detection of bacterial endotoxins in Honghua for intravenous drip.
Keywords:Bacterial endotoxin  Tachypleus amebocyte lysate (TAL)  Honghua injection
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