Use of A Continuous Glucose Monitor in the Management of Inoperable Meta Static Insulinoma: A Case Report |
| |
| Affiliation: | 1. College of Mathematics and Information Science, Xinyang Normal University, Xinyang 464000, PR China;2. Academy of Mathematics and Systems Science, Chinese Academy of Science, Beijing 100080, PR China;1. Division of Emergency Medicine, Newton-Wellesley Hospital, Newton, MA;2. Emory University, Children''s Healthcare of Atlanta, Atlanta, GA;3. Boulder Statistics, LLC, Boulder, CO;4. Seton University of Texas Southwestern Clinical Research Institute, University Medical Center at Brackenridge, Austin, TX;5. Dell Children''s Medical Center, Austin, TX;6. Scottish Rite Hospital, Children''s Healthcare of Atlanta, Atlanta, GA;7. Children''s Medical Center, Dallas, TX;8. Dell Children''s Medical Center, Austin, TX;9. Venaxis, Inc, Castle Rock, CO;1. Department of Wildlife Ecology and Conservation, Tropical Conservation and Development Program, University of Florida, United States;2. Department of Agricultural and Resource Economics, University of California, Davis, United States;1. School of Microelectronics, Shanghai Jiao Tong University, 800 Dongchuan Road,Shanghai 200240, P.R. China;2. Department of Electrical and Computer Engineering, National University of Singapore, 21 Lower Kent Ridge Road, Singapore;3. Department of Computer Science, Pace University, 1 Pace Plaza, Manhattan, New York City, NY, 10038, USA;4. Shanghai Key Laboratory of Data Science, Fudan University, 825 Zhangheng Road, Shanghai 201203, P.R. China;5. PLA Information Engineering University, P.R. China;6. School of Computing, National University of Singapore, Singapore;2. Department of Agricultural Economics, Mississippi State University, Mississippi State 39762 |
| |
| Abstract: | ObjectiveTo describe the successful use of a continuous glucose monitor in the management of a patient with inoperable metastatic insulinoma.MethodsWe present a case of inoperable recurrent metastatic insulinoma in which medical therapy failed to relieve symptoms of dangerous hypoglycemia. We describe how the use of a continuous glucose monitor has assisted in avoiding hypoglycemia and improving her quality of life.ResultsA 70-year-old woman with a history of recurrent surgically treated insulinoma presented with recurrent hypoglycemia secondary to multiple metastases in the liver. Diazoxide therapy decreased the frequency of symptoms, but she continued to have hypoglycemic episodes resulting in frequent visits to the emergency department. Since starting to use a continuous glucose monitor, she has been able to avoid hypoglycemia with associated neuroglycopenic symptoms. While the accuracy of the device was poor when compared with conventional fingerstick monitors, the sensor tended to read higher than the meter in the hypoglycemic range. Although this led to more frequent false-positive hypoglycemic alarms, true episodes of severe hypoglycemia were rare.ConclusionsMalignant insulinomas are rare tumors. Many affected patients have disease that is unresectable, and medical therapy is limited in its ability to prevent hypoglycemic episodes. We have demonstrated that a continuous glucose monitor can be a useful adjunct to therapy to reduce hypoglycemic episodes by alerting the patient to low glucose concentrations before the development of neuroglycopenic symptoms. (Endocr Pract. 2008;14:880-883) |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
