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某市自来水有机提取物对小鼠精子及血清睾酮含量影响的研究
引用本文:田怀军,吴德生,李荣江,杜慧兰,陶锐,汪良吉.某市自来水有机提取物对小鼠精子及血清睾酮含量影响的研究[J].环境与健康杂志,1999,16(2):74-76.
作者姓名:田怀军  吴德生  李荣江  杜慧兰  陶锐  汪良吉
作者单位:1. 华西医科大学公共卫生学院环卫教研室,成都,610041
2. 四川省成都市防疫站
3. 四川省成都市卫生局
摘    要:为探讨饮用水中有机提取物的生殖毒性,研究了某市自来水有机提取物对小鼠精子和血清睾酮含量的影响。结果表明:染毒后10天,有机提取物致使精子活性降低畸开 子数增加,梁毒后35天,精子活性、血清睾酮含量均显著下降。说明该自来水有机提取物通过血-睾屏障,干扰生精细胞正常发育。

关 键 词:饮用水  有机污染物  提取物  睾酮  生殖毒性
修稿时间:1998年9月9日

The Effects of Organic Extract From Drinking Water on the Sperm and the Levels of Serum Testosterone in Male Mice
Tian Huaijun,Wu Desheng,Li Rongjiang et al.West China Unviersity of Medicine Science,Chengdu.The Effects of Organic Extract From Drinking Water on the Sperm and the Levels of Serum Testosterone in Male Mice[J].Journal of Environment and Health,1999,16(2):74-76.
Authors:Tian Huaijun  Wu Desheng  Li Rongjiang West China Unviersity of Medicine Science  Chengdu
Affiliation:Tian Huaijun,Wu Desheng,Li Rongjiang et al.West China Unviersity of Medicine Science,Chengdu 610041
Abstract:To study the toxicity of organic extract from drinking water on the reproduction system,the effects of organic extract from drinking water on the sperms and the levels of serum testosterone in male mice were observed in the present study.The results showed that:at 10 th day after exposure(i.p.),the organic extract produced significant decrease in the activity of sperms and inerease in the amount of teratospermia;at 35 th day after exposure significant decrease in the activity and density of sperms and the leves of serum testosterone.It indicated that the organic extracts from drinking water could pass through the blood testicle barrier and induce abnormalities in spermatogenic cells.
Keywords:Drinking water  Organic pollutants  Extracts  Testoserone  Reproductive toxicity  
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