| 灵芝孢子滴眼液对辐射性兔眼防护作用的研究 |
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| 引用本文： | 郭曙光,李英琴,张雅莉,唐瞬,张春蕾,崔秀梅.灵芝孢子滴眼液对辐射性兔眼防护作用的研究[J].中国现代中药,2008,10(11):34-36. |
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| 作者姓名： | 郭曙光 李英琴 张雅莉 唐瞬 张春蕾 崔秀梅 |
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| 作者单位： | 1. 黑龙江中医药大学佳木斯学院,黑龙江,佳木斯,154005
2. 中国药材集团公司科技研发部,北京,100195 |
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| 基金项目： | 黑龙江中医药、中西医结合重点科研项目 |
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| 摘 要： | 目的：探讨灵芝孢子滴眼液对兔眼辐射性损伤的作用和房水中相关酶活性的影响。方法：将破壁灵芝孢子制剂成滴眼液。选取黑眼睛健康獭兔30只随机分成5组，每组6只。1组为空白对照组；另4组采取每日2次紫外线辐射，每次辐射40min，其中3组为高、中、低浓度灵芝孢子滴眼液试验组，每日滴眼药3次；1组不用药为辐射模型组。试验60d。分别检测兔眼房水中超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GSH—Px）的活性和丙二醛（MDA）的含量；在光学显微镜下观察兔眼角膜结构的变化及细胞分布情况。结果：辐射滴眼药组兔眼房水中SOD和GSH．Px活性较辐射模型组明显升高，MDA含量明显降低，角膜组织结构紧密连续且形态完整。结论：灵芝孢子滴跟液对辐射性兔眼具有保护作用。
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| 关 键 词： | 灵芝孢子滴眼液 射频辐射 辐射性损伤 |
| 收稿时间： | 2008/5/15 0:00:00 |
Ganoderma Lucidum on Eye Drops Radioactive Protective Role of Rabbit Study |
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| Guo Shuguang,Li Yingqin,Zhang Yali,Tang Shun,Zhang Chunlei and Cui Xiumei.Ganoderma Lucidum on Eye Drops Radioactive Protective Role of Rabbit Study[J].Modern Chinese Medicine,2008,10(11):34-36. |
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| Authors: | Guo Shuguang Li Yingqin Zhang Yali Tang Shun Zhang Chunlei and Cui Xiumei |
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| Affiliation: | Guo Shuguang~(1*) Li Yingqin~1 Zhang Yali~1 Tang Shun~1 Zhang Chunlei~1 Cui Xiumei~2 (1.School of jiamusi,Heilongjiang University of Traditional Chinese Medicine,Jiamusi Hei longjiang 154005,China,2.Research & Development Center,China National Group Crop.of Tradicinal & Herbal Medicine,Beijing 100195,China) |
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| Abstract: | Objective:To discuss effects of Ganoderma Lucidum Spores eyedrop(GLSED)on the radiation in- jury and the activity of associated Enzymes in aqueous humor on rabbit eyes.Methods:To make Ganoderma Lucidum Spores into eyedrop,to select 30 healthy rexrabbits of black eye,then divided into 5 groups randomly:One control group and four treatment group,which ones were carried by ultraviolet radiation without drug,others taked the drug which divided three different dose medication-administration groups by ultraviolet... |
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| Keywords: | Ganoderma lucidum Spores eyedrop Radio-frequency radiation Radiation injury edicinealt |
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