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感冒退热泡腾片的干法制粒工艺研究
引用本文:饶小勇,黄恺,张国松,张尧,罗晓健.感冒退热泡腾片的干法制粒工艺研究[J].中草药,2009,40(12):1890-1893.
作者姓名:饶小勇  黄恺  张国松  张尧  罗晓健
作者单位:中药固体制剂制造技术国家工程研究中心;江西中医学院;中药固体制剂制造技术国家工程研究中心;中药固体制剂制造技术国家工程研究中心;中药固体制剂制造技术国家工程研究中心;江西中医学院
摘    要:目的 研究感冒退热泡腾片干法制粒的工艺条件.方法 考察压轮压力、压轮转速和浸膏粉含水量对颗粒得率和颗粒脆碎度的影响.结果 压轮压力、压轮转速和浸膏粉含水量对颗粒得率和颗粒脆碎度有显著性影响.结论 感冒退热泡腾片干法制粒工艺的研究为感冒退热泡腾片研究与生产提供技术参考.

关 键 词:感冒退热泡腾片  干法制粒  压轮压力  压轮转速  含水量
收稿时间:5/6/2009 12:00:00 AM

Preparation of Ganmao Tuire effervescent tablets by dry granulation
RAO Xiao-yong,HUANG Kai,ZHANG Guo-song,ZHANG Yao and LUO Xiao-jian.Preparation of Ganmao Tuire effervescent tablets by dry granulation[J].Chinese Traditional and Herbal Drugs,2009,40(12):1890-1893.
Authors:RAO Xiao-yong  HUANG Kai  ZHANG Guo-song  ZHANG Yao and LUO Xiao-jian
Affiliation:National Pharmaceutical Engineering Center for Soild Preparation in Chinese Herbal Medicine, Nanchang 330006, China;Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China;National Pharmaceutical Engineering Center for Soild Preparation in Chinese Herbal Medicine, Nanchang 330006, China;National Pharmaceutical Engineering Center for Soild Preparation in Chinese Herbal Medicine, Nanchang 330006, China;National Pharmaceutical Engineering Center for Soild Preparation in Chinese Herbal Medicine, Nanchang 330006, China;Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China
Abstract:Objective To optimize the best preparation condition of Ganmao Tuire effervescent tablets by dry granulation.Methods The influence of roller pressure,roller speed,and water content of extract powder on yield and friabi lity of particle diameter was investigated.Results The roller pressure,roller speed,and water content of extract powder had a significant influence on yield and friability of particles.Conclusion The preparation investigation of Ganmao Tuire effervescent tablets provides the reference technology to study and production for Ganmao Tuire effervescent tablets.
Keywords:Ganmao Tuire effervescent tablets  dry granulation  roller pressure  roller speed  water content
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