| 新生儿缺氧缺血性脑病血浆ET和CGRP测定及临床意义 |
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| 引用本文： | 刘辉,王海峰,朱红岩,仇为民,陈晶.新生儿缺氧缺血性脑病血浆ET和CGRP测定及临床意义[J].放射免疫学杂志,2007,20(6):505-506. |
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| 作者姓名： | 刘辉 王海峰 朱红岩 仇为民 陈晶 |
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| 作者单位： | 1. 江苏省连云港市第一人民医院东方医院,222042
2. 连云港市第一人民医院临床检验中心 |
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| 摘 要： | 目的:探讨新生儿缺氧缺血性脑病患者血浆内皮素(ET)和降钙素基因相关肽(CGRP)水平的变化及临床意义.方法:应用放射免疫分析检测了符合诊断标准的观察组缺氧缺血性脑病新生儿68例,及对照组同期健康新生儿30例血浆中ET和CGRP水平,并做了比较.结果:观察组血浆ET水平显著的高于对照组,而CGRP水平显著的低于对照组.结论:新生儿缺氧缺血性脑病的发生发展与ET和CGRP水平的变化密切相关.
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| 关 键 词： | 新生儿缺氧缺血性脑病(HIE) 内皮素(ET) 降钙素基因相关肽(CGRP) |
| 收稿时间： | 2007-10-11 |
| 修稿时间： | 2007年10月11 |
Clinical Significance of Determination of Changes of Plasma ET and CGRP Contents in Neonates with Hypoxic-Ischemic Encephalopathy |
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| Liu Hui, Wang Haifeng, Zhu Hongyan,et al..Clinical Significance of Determination of Changes of Plasma ET and CGRP Contents in Neonates with Hypoxic-Ischemic Encephalopathy[J].Journal of Radioimmanology,2007,20(6):505-506. |
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| Authors: | Liu Hui Wang Haifeng Zhu Hongyan |
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| Abstract: | Objective To investigate the clinical significance of changes of plasma ET and CGRP levels in neonates with hypoxic-ischemic encephalopathy (HIE). Methods Plasma ET and CGRP contents were determined with RIA in 68 neonates with hypoxic-ischemic encephalopathy and 30 controls. Results In neonates with HIE, the plasma ET levels were significantly higher than those in the controls (P<0.01), while the plasma CGRP levels were significantly lower(P<0.01). Conclusion Development of hypoxic-ischemic encephalopathy in newborn infants was closely related to the plasma ET and CGRP levels. |
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| Keywords: | hypoxic-ischemic encephalopathy(HIE) endothelin (ET) calcitonim gene-related peptide (CGRP) |
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