| 基于Matlab的甲壳动物线粒体DNA的点突变检测方法 |
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| 引用本文： | 耿帅,韩磊,盂娇.基于Matlab的甲壳动物线粒体DNA的点突变检测方法[J].淮海工学院学报,2012(1):25-28. |
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| 作者姓名： | 耿帅 韩磊 盂娇 |
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| 作者单位： | [1]中国矿业大学信息与电气工程学院,江苏徐州221116 [2]淮海工学院电子工程学院．江苏连云港222005,江苏徐州221116 |
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| 基金项目： | 江苏省海洋资源开发研究院开放课题（JSIMR09C07）}淮海工学院江苏省海洋生物技术重点建设实验室开放课题（2009HS12） |
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| 摘 要： | 近年来对基因突变检测的研究越来越受到人们的重视，很多基因突变仅是由于单碱基替换所致，如何快速简便地进行检测、发现该点突变具有重要意义’。甲壳动物的线粒体基因组蕴含了物种进化历程中重要的遗传信息，针对甲壳动物线粒体基因序列，提出一种基于Matlab的检测基因序列点突变的简单方法。仿真实验证明，该方法对甲壳动物线粒体基因序列的突变检测和突变基因位置的定位是有效可行的。
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| 关 键 词： | Matlab GUI 基因序列 基因突变 点突变 |
Point Mutation Detection Method Based on Matlab of Crustacean Mitochondria DNA |
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| Affiliation: | GENG Shuai, HAN Lei, MENG Jiao School of Information and Electrical Engineering, China University of Mining and Technology, Xuzhou 221116, China; 2. School of Electrical Engineering, Huaihai Institute of Technology, Lianyungang 222005, China) |
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| Abstract: | In recent years, more and more attention has been paid to studies on gene mutations. Many gene mutations are only caused by the single base substitution, and how to detect and find this kind of point mutation quickly and easily has great significance. Crustacean mitochondrial ge- home contains the important genetic information of species evolution. For the mitochondrial gene sequence of crustaceans, this paper presents a simple point mutation detection method based Mat- lab. The simulation results prove this method to be feasible and effective for detecting the muta- tion and locating the mutation gene of the mitochondrial gene sequence of crustaceans. |
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| Keywords: | Matlab GUI gene sequence gene mutation point mutation |
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