基质金属蛋白酶-2与脑血管畸形关系的研究 |
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引用本文: | 刘子科,林智敏,许海珍,兰周华,董广宇,吴春波,林锦波,杨亚敏,黄翔.基质金属蛋白酶-2与脑血管畸形关系的研究[J].吉林医学,2011(19):3887-3888. |
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作者姓名: | 刘子科 林智敏 许海珍 兰周华 董广宇 吴春波 林锦波 杨亚敏 黄翔 |
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作者单位: | 广东省深圳市龙岗区人民医院 |
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摘 要: | 目的:研究基质金属蛋白酶-2(MMP-2)与脑血管畸形的关系。方法:选择脑血管畸形患者50例作为观察组,同时选择50例体检中心的正常人作为对照组,取两组患者的血液,对比MMP-2水平。结果:观察组血清MMP-2水平在发病第1天、第7天和第14天均明显高于对照组(P<0.05),而且观察组血清MMP-2水平在第7天明显高于第1天和第14天(P<0.05)。结论:MMP-2的表达异常与脑血管畸形呈正相关关系。
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关 键 词: | 基质金属蛋白酶-2 脑血管畸形 |
Relation between matrix metalloproteinase 2 and cerebral vascular malformations |
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Affiliation: | LIU Zi-ke,LIN Zhi-min,XU Hai-zhen,et al(The People′s Hospital of Longgang District,Shenzhen 518172,China) |
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Abstract: | Objective To study the relation between matrix metalloproteinase 2(MMP-2) and the cerebral vascular malformations.Method The patients with cerebral vascular malformations was selected as the experimental group(n=50),and 50 healthy adults as the control group(n=50).The level of MMP-2 in the blood between the two groups was contrasted.Results The levels of MMP-2 in the experimental group exceeded which of the control group on the first,the seventh and the fourteenth day after the onset(P0.05).And within the experimental group,the levels of MMP-2 on the seventh day exceeded which on the first,the fourteenth day after the onset(P0.05).Conclusion The level of MMP-2 has positive correlation with the cerebral vascular malformations. |
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Keywords: | MMP-2 Cerebral vascular malformations |
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