老年糖尿病患者肠道菌群变化的相关因素分析

目的：探讨老年2型糖尿病肠道菌群变化的危险因素。方法：选我院老干部科60例65-89岁2型糖尿病人,取新鲜粪便,选择肠道菌群中3种具有代表性的细菌进行计数。然后根据病程长短、有无微量蛋白尿、糖化血红蛋白高低分别分成两组进行统计学分析。结果：病程〉10年、有微量尿蛋白、糖化血红蛋白（7.1±1.31）%的患者,双歧杆菌数量减少（P〈0.05）。结论：老年糖尿病的病程和有无并发症、血糖控制情况均对肠道菌群有影响。

Clinic Analysis of the Changes of Intestinal Flora and its Related Factors in the Elderly Diabetes

Objective： To explore the related factors of the changes of intestinal flora in the elderly diabetes with type 2. Methods：55 elderly diabetes, Feces samples of all cases were cultured under both aerobic and anaerobic conditions for the 3 bacteria. The relation ship between the quantity change of intestinal micro flora and various factor such as course of disease, glycosylated hemoglobin（HBALC）, have or no urinary albumin were analyed. Results： Course of disease 〉 10 years, glycosylated hemoglobin （HBALC） （7.1 ± 1.31 ） % have urinary albumin（LIALB）. The quantity of bifidobacterum were significantly decreased （P 〈 0.05 ）. Conclusion： Course of disease, glycemic control and have or no complications have differential factors to intestinal flore in the elderly diabetes.