| 174株结核分枝杆菌耐药情况分析 |
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| 引用本文： | 李妍,王西娣,陈美玲,杨健.174株结核分枝杆菌耐药情况分析[J].临床肺科杂志,2014,0(8):1460-1462. |
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| 作者姓名： | 李妍 王西娣 陈美玲 杨健 |
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| 作者单位： | 李妍 (陕西省结核病防治研究所, 陕西 西安,710048)； 王西娣 (陕西省结核病防治研究所, 陕西 西安,710048)； 陈美玲 (陕西省结核病防治研究所, 陕西 西安,710048)； 杨健 (陕西省结核病防治研究所, 陕西 西安,710048)； |
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| 摘 要： | 目的分析我所183株痰培养阳性菌株的耐药情况。方法采用药敏比例法对183株阳性菌株进行菌种鉴定及药物敏感性试验。结果共分离出174株结核分枝杆菌,且4种一线抗结核药物异烟肼(INH)、利福平(RFP)、乙胺丁醇(EMB)、链霉素(SM)的总耐药率为25.3%,耐多药率为8.0%。4种抗结核药物的耐药率由高到低依次为SM、INH、EMB、RFP。结论陕西省结核耐药情况仍较严重。
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| 关 键 词： | 结核分枝杆菌 药物敏感试验 耐药结核病 |
Analysis of drug resistance of 174 strains of Mycobacterium tuberculosis |
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| LI Yan;WANG Xi-di;CHEN Meiling;YANG Jian.Analysis of drug resistance of 174 strains of Mycobacterium tuberculosis[J].Journal of Clinical Pulmonary Medicine,2014,0(8):1460-1462. |
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| Authors: | LI Yan;WANG Xi-di;CHEN Meiling;YANG Jian |
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| Affiliation: | LI Yan;WANG Xi-di;CHEN Meiling;YANG Jian;(Shanxi Provincial Institute for TB Control and Prevention;) |
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| Abstract: | Objective To analyze the status of drug resistance in 183 cases of the sputum culture-positive strains isolated in our institute. Methods The proportional method was used in bacteria identification and drug sensitivity tests of 183 strains. Results 174 strains of Mycobacterium tuberculosis were isolated,and the total drug resistance rate to 4 first-line anti tuberculosis drugs（ INH,RFP,EMB,SM） was 25. 3% and their multi drug resistant rate was 8. 0%. It showed the highest resistance to SM,followed by INH,EMB and RFP. Conclusion The drug resistance of Mycobacterium tuberculosis in Shanxi province is still serious. |
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| Keywords: | Mycobacterium tuberculosis drug-susceptibility testing drug-resistant tuberculosis |
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