青少年不宁腿综合征与自杀行为的关系

目的 探究青少年不宁腿综合征和自杀行为间的关系。 方法 在山东省三县(市)采用方便整群抽样的方式共选取5所初中和3所高中作为目标学校,调查对象为来自目标学校的7~11年级学生,发放问卷收集相关资料,包括研究对象的一般人口学信息、不宁腿综合征、自杀行为、抑郁和失眠等信息,共收集有效调查问卷11 831份。采用多因素Logistic回归模型分析不宁腿综合征和自杀行为的关系。 结果 11 831名研究对象的平均年龄为(14.97±1.46)岁,49.1%是女性。不宁腿综合征组的自杀行为(33.3% vs 21.6%,P<0.05)、自杀意念(29.7% vs 19.5%,P<0.05)、自杀计划(15.2% vs 9.0%,P<0.05)和自杀未遂(7.0% vs 3.6%,P<0.05)的报告率均高于非不宁腿综合征组。调整其他潜在混杂因素后,多因素Logistic回归分析显示不宁腿综合征与自杀行为(OR=1.36, 95%CI=1.18~1.57)、自杀意念(OR=1.25, 95%CI=1.08~1.46)、自杀计划(OR=1.26, 95%CI=1.04~1.52)和自杀未遂(OR=1.35, 95%CI=1.03~1.76)的关联均具有统计学意义。 结论 在青少年中,不宁腿综合征和自杀行为间存在关联。

Association between restless legs syndrome and suicidal behaviors among adolescents

Objective To explore the association between restless legs syndrome(RLS)and suicidal behaviors in a large sample of Chinese adolescents. Methods A total of 11 831 adolescents were included in the analysis. The 7-11 graders were sampled from 5 middle schools and 3 high schools in 3 counties of Shandong Province, China. A self-administrated structured questionnaire was used to collect information about demographics, RLS, suicidal behaviors, depression and insomnia. Logistic regression analyses were performed to examine the association between RLS and suicidal behaviors. Results Of the 11 831 participants, the average age was(14.97±1.46)years and 49.1% were girls. The prevalence of suicidal behaviors(33.3% vs 21.6%, P<0.05), suicidal ideation(29.7% vs 19.5%, P<0.05), suicide plan(15.2% vs 9.0%, P<0.05)and suicide attempt(7.0% vs 3.6%, P<0.05)were higher in adolescents with RLS than in those without. Multivariate Logistic regressions showed that RLS was associated with suicidal behaviors(OR=1.36, 95%CI=1.18-1.57), suicidal ideation(OR=1.25, 95%CI=1.08-1.46), suicide plan(OR=1.26, 95%CI=1.04-1.52), and suicide attempt(OR=1.35, 95%CI=1.03-1.76). Conclusion RLS is associated with suicidal behaviors among adolescents.