冠心病患者检测hs—CRP的临床价值

目的探讨冠心病患者检测超敏C反应蛋白（hs—CRP）的临床意义。方法选择54例稳定型心绞痛患者（SAP）、71例不稳定型心绞痛患者（UAP）、43例急性心肌梗死患者（AMI）与这43例处于恢复期的急性心肌梗死患者．检测其血清hs—CRP水平，与65例健康者对照比较。结果SAP、UAP、AMI三组患者血清hs—CRP水平依次逐渐升高。AMI恢复期患者血清hs—CRP水平同AMI组比较显著降低（P〈0．01）。4组患者hs—CRP水平同健康对照组比较均显著性升高（P〈0．01）。结论冠心病患者血清hs—CRP水平升高与其病情严重程度呈正相关，提示hs—CRP不仅是冠心病的一种危险因子．而且与冠心病预后密切相关。

Clinical value of hs-CRP detection in patients with coronary heart disease

Objective To investigate the clinical significance of the detection of hs-CRP in patients with coronary heart disease. Methods 54 patients with stable angina pectoris （SAP）,71 patients with unstable angina pectorls （UAP）,43 patients with acute myocardial infarction （AMI） and AMI patients in recovery phase were detected the serum hs-CRP levels, compared with 65 healthy persons as control group. Results Serum hs-CRP levels of SAP,UAP and AMI groups rose successively. Compared with AMI group, serum hs-CRP level of AMI in recovery phase reduced significantly （P〈0.01）.Serum hs-CRP levels of 4 groups rose significantly compared with control group （P〈0.01）. Conclusion Serum hs-CRP levels rising is positively correlated with illness severity. Suggested that hs-CRP is not only a risk factor for coronary heart disease,but is closely related to coronary heart disease prognosis.