Liver phospholipid distribution in hypophysectomized catfish, Clarias batrachus and Heteropneustes fossilis

As with any specialized diagnostic technique, the degree of success and safety of needle biopsy of the thyroid are largely based on experience. While an adequate core of tissue for examination is imperative, the interpretation by the pathologist is equally important. A close liaison of the latter with his clinical colleagues is necessary for optimal pathologic evaluation. A review of this experience during a 20 year period shows that needle biopsy is a reliable diagnostic procedure in more than 90 per cent of the patients. It is unlikely to disseminate the disease or compromise the prognosis, and it is a safe office procedure.