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首发抑郁症患者糖代谢的研究
引用本文:夏青春,王高华,陈海支,陈小陨,那万秋.首发抑郁症患者糖代谢的研究[J].浙江大学学报(医学版),2011,40(2).
作者姓名:夏青春  王高华  陈海支  陈小陨  那万秋
作者单位:湖州市第三人民医院,浙江湖州,313000
摘    要:目的:探讨首发抑郁症患者的糖代谢情况。方法:对100例首发抑郁症患者及50名健康人进行糖耐量试验(OGTT),并检测其空腹血浆胰岛素的浓度。结果:餐后0 h、餐后1 h、餐后3h血糖值,两组间差异均无统计学意义(P>0.05);抑郁症组空腹血糖值、餐后2 h的血糖值、OGTT血糖曲线下面积,两组比较均有显著性统计学差异(P<0.01);两组糖耐量减退的发生率有显著性统计学差异(P<0.01),抑郁症组糖耐量减退发生率较对照组高。结论:首发抑郁症患者存在一定的糖代谢异常,临床医师应该对抑郁症患者的血糖进行随访监测,以便早期发现、干预、治疗糖代谢性疾病。

关 键 词:抑郁症/代谢  血糖  葡萄糖/代谢  葡萄糖耐量试验  首发抑郁症  糖耐量减退  

Glycometabolism of patients with depression at first episode
XIA Qing-chun,WANG Gao-hua,CHEN Hai-zhi,CHEN Xiao-yun,NA Wan-qiu.Glycometabolism of patients with depression at first episode[J].Journal of Zhejiang University(Medical Sciences),2011,40(2).
Authors:XIA Qing-chun  WANG Gao-hua  CHEN Hai-zhi  CHEN Xiao-yun  NA Wan-qiu
Affiliation:XIA Qing-chun,WANG Gao-hua,CHEN Hai-zhi,CHEN Xiao-yun,NA Wan-qiu(The Third People's Hospital of Huzhou,Huzhou 313000,China)
Abstract:Objective:To investigate glycometabolism of patients with depression at first episode. Methods:Oral glucose tolerance test(OGTT) was performed in 100 patients with depression at first episode and 50 healthy subjects;the levels of fast blood plasma insulin were also measured. Results:There were no statistically significant differences in fast blood plasma insulin levels and postprandial blood glucose levels at 0 h,1 h and 3 h(P>0.05);the fasting blood glucose(FBS),postprandial blood glucose levels in 2 h and...
Keywords:Depressive disorder/metabol  Blood glucose  Glucose/metabol  Glucose tolerance test  First episode depression  Impaired glucose tolerance(IGT)  
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