| 胶质母细胞瘤的治疗策略 |
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| 引用本文： | 舒晓宏.胶质母细胞瘤的治疗策略[J].大连医科大学学报,2020,42(6):481-486. |
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| 作者姓名： | 舒晓宏 |
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| 作者单位： | 大连医科大学 药学院 药物化学教研室, 辽宁 大连 116044 |
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| 基金项目： | 国家自然科学基金项目（81672945，81072063）；辽宁省自然科学基金项目（201602234）；中国博士后科学基金项目（20100481217） |
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| 摘 要： | 胶质母细胞瘤（glioblastoma multiforme，GBM）是一种破坏性极强、难以治愈的神经系统肿瘤。临床治疗以手术切除为主，并结合放疗、化疗及电场治疗等多种治疗手段。但GBM侵袭性强、手术难以彻底根除，故患者预后差、死亡率居高不下。因此，延长患者生存时间并提升其生存质量一直是GBM治疗的重要目标。本文将基于GBM治疗策略加以探讨。
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| 关 键 词： | 胶质母细胞瘤 手术切除 放射治疗 化学治疗 电场治疗 |
| 收稿时间： | 2020/11/30 0:00:00 |
| 修稿时间： | 2020/12/1 0:00:00 |
Therapeutic strategies for glioblastoma |
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| SHU Xiaohong.Therapeutic strategies for glioblastoma[J].Journal of Dalian Medical University,2020,42(6):481-486. |
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| Authors: | SHU Xiaohong |
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| Affiliation: | Department of Pharmaceutical Chemistry, College of Pharmacy, Dalian Medical University, Dalian 116044, China |
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| Abstract: | Glioblastoma (GBM) is a very destructive nervous system tumor, and it is almost incurable. The clinical therapeutic strategies of GBM mainly include surgical resection, combined with radiotherapy, chemotherapy, tumor treating fields and other treatments. GBM is difficult to eradicate by surgery for its strong invasion, so the prognosis of patients is poor and the mortality rate is high. Therefore, prolonging the survival time and improving the life quality of patients have been the important goals of GBM treatment, and this paper will focus on the treatment strategy for GBM. |
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| Keywords: | glioblastoma multiforme surgical resection radiotherapy chemotherapy tumor treating fields |
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