| 广东省鳜鱼和杂交鳢中孔雀石绿和硝基呋喃残留调查及暴露评估 |
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| 引用本文： | 刘书贵,尹怡,单奇,郑光明,陈昆慈,朱新平,马丽莎,戴晓欣.广东省鳜鱼和杂交鳢中孔雀石绿和硝基呋喃残留调查及暴露评估[J].中国食品卫生杂志,2015,27(5):553-558. |
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| 作者姓名： | 刘书贵 尹怡 单奇 郑光明 陈昆慈 朱新平 马丽莎 戴晓欣 |
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| 作者单位： | 中国水产科学研究院珠江水产研究所 农业部热带亚热带水产种质资源利用与养殖重点实验室 农业部水产品质量安全风险评估实验室广州,广东 广州 510380,中国水产科学研究院珠江水产研究所 农业部热带亚热带水产种质资源利用与养殖重点实验室 农业部水产品质量安全风险评估实验室广州,广东 广州 510380,中国水产科学研究院珠江水产研究所 农业部热带亚热带水产种质资源利用与养殖重点实验室 农业部水产品质量安全风险评估实验室广州,广东 广州 510380,中国水产科学研究院珠江水产研究所 农业部热带亚热带水产种质资源利用与养殖重点实验室 农业部水产品质量安全风险评估实验室广州,广东 广州 510380,中国水产科学研究院珠江水产研究所 农业部热带亚热带水产种质资源利用与养殖重点实验室 农业部水产品质量安全风险评估实验室广州,广东 广州 510380,中国水产科学研究院珠江水产研究所 农业部热带亚热带水产种质资源利用与养殖重点实验室 农业部水产品质量安全风险评估实验室广州,广东 广州 510380,中国水产科学研究院珠江水产研究所 农业部热带亚热带水产种质资源利用与养殖重点实验室 农业部水产品质量安全风险评估实验室广州,广东 广州 510380,中国水产科学研究院珠江水产研究所 农业部热带亚热带水产种质资源利用与养殖重点实验室 农业部水产品质量安全风险评估实验室广州,广东 广州 510380 |
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| 基金项目： | 水产品养殖禁限用药物调查与产品安全性评估(GJFP201501001)；淡水经济鱼类新品种选育(2012BAD26B03) |
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| 摘 要： | 目的了解广东省主要养殖地的鳜鱼和杂交鳢中孔雀石绿及其代谢物和硝基呋喃类代谢物的残留情况。方法利用高效液相色谱-串联质谱法对鱼肉中的孔雀石绿及其代谢物和硝基呋喃类代谢物残留量进行测定。结果2013年孔雀石绿的总检出率为11.7%,硝基呋喃类代谢物的总检出率为20%。2014年孔雀石绿的总检出率为25%,硝基呋喃类代谢物的总检出率为12.5%。近两年总孔雀石绿残留量在0.58~19.1μg/kg之间,总硝基呋喃类代谢物残留量在0.66~36.6μg/kg之间。暴露评估显示:人体每天可能的孔雀石绿的平均暴露量0.24μg,即每人每日膳食暴露量为0.004μg/kg BW,最高暴露量1.10μg,即每人每日膳食暴露量为0.02μg/kg BW;人体可能的每天呋喃西林代谢物的平均暴露量为0.34μg,即每人每日膳食暴露量为0.005μg/kg BW,最高暴露量为0.87μg,即每人每日膳食暴露量为0.01μg/kg BW;人体可能的每天呋喃唑酮代谢物的平均暴露量0.56μg,即每人每日膳食暴露量为0.009μg/kg BW,最高暴露量2.10μg,即每人每日膳食暴露量为0.03μg/kg BW。结论近两年鳜鱼和杂交鳢中孔雀石绿和硝基呋喃类检出率相对较低,膳食暴露评估显示孔雀石绿在此范围内对人体健康损害危险性极小。
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| 关 键 词： | 孔雀石绿 硝基呋喃代谢物 养殖 鱼 膳食暴露评估 广东 兽药残留 违禁药物 水产品 |
| 收稿时间： | 2015/5/23 0:00:00 |
Residual levels of malachite green and nitrofuran metabolites in farmed fish from Guangdong and exposure assessment |
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| LIU Shu-gui,YIN Yi,SHAN Qi,ZHENG Guang-ming,CHEN Kun-ci,ZHU Xin-ping,MA Li-sha and DAI Xiao-xin.Residual levels of malachite green and nitrofuran metabolites in farmed fish from Guangdong and exposure assessment[J].Chinese Journal of Food Hygiene,2015,27(5):553-558. |
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| Authors: | LIU Shu-gui YIN Yi SHAN Qi ZHENG Guang-ming CHEN Kun-ci ZHU Xin-ping MA Li-sha and DAI Xiao-xin |
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| Affiliation: | Ministry of Agriculture/Ministry of Agriculture Laboratory of Quality & Safety Risk Assessment for Aquatic Product Guangzhou ,Key Laboratory of Tropical & Subtropical Fishery Resource Application & Cultivation,Pearl River Fisheries Institute,Chinese Academy of Fishery Sciences, Guangdong Guangzhou 510380,China,Ministry of Agriculture/Ministry of Agriculture Laboratory of Quality & Safety Risk Assessment for Aquatic Product Guangzhou ,Key Laboratory of Tropical & Subtropical Fishery Resource Application & Cultivation,Pearl River Fisheries Institute,Chinese Academy of Fishery Sciences, Guangdong Guangzhou 510380,China,Ministry of Agriculture/Ministry of Agriculture Laboratory of Quality & Safety Risk Assessment for Aquatic Product Guangzhou ,Key Laboratory of Tropical & Subtropical Fishery Resource Application & Cultivation,Pearl River Fisheries Institute,Chinese Academy of Fishery Sciences, Guangdong Guangzhou 510380,China,Ministry of Agriculture/Ministry of Agriculture Laboratory of Quality & Safety Risk Assessment for Aquatic Product Guangzhou ,Key Laboratory of Tropical & Subtropical Fishery Resource Application & Cultivation,Pearl River Fisheries Institute,Chinese Academy of Fishery Sciences, Guangdong Guangzhou 510380,China,Ministry of Agriculture/Ministry of Agriculture Laboratory of Quality & Safety Risk Assessment for Aquatic Product Guangzhou ,Key Laboratory of Tropical & Subtropical Fishery Resource Application & Cultivation,Pearl River Fisheries Institute,Chinese Academy of Fishery Sciences, Guangdong Guangzhou 510380,China,Ministry of Agriculture/Ministry of Agriculture Laboratory of Quality & Safety Risk Assessment for Aquatic Product Guangzhou ,Key Laboratory of Tropical & Subtropical Fishery Resource Application & Cultivation,Pearl River Fisheries Institute,Chinese Academy of Fishery Sciences, Guangdong Guangzhou 510380,China,Ministry of Agriculture/Ministry of Agriculture Laboratory of Quality & Safety Risk Assessment for Aquatic Product Guangzhou ,Key Laboratory of Tropical & Subtropical Fishery Resource Application & Cultivation,Pearl River Fisheries Institute,Chinese Academy of Fishery Sciences, Guangdong Guangzhou 510380,China and Ministry of Agriculture/Ministry of Agriculture Laboratory of Quality & Safety Risk Assessment for Aquatic Product Guangzhou ,Key Laboratory of Tropical & Subtropical Fishery Resource Application & Cultivation,Pearl River Fisheries Institute,Chinese Academy of Fishery Sciences, Guangdong Guangzhou 510380,China |
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