维生素加早期干预对早产低出生体重儿智能发育的影响

目的:了解维生素加早期干预对早产低出生体重儿智能发育的影响。方法:选择2001年12月～2003年12月出生存活的早产儿160例随机分为维生素加干预组和早产对照组,同时收集正常出生体重儿80例为足月对照组。干预组在新生儿期即给予抚触、听背景音乐、看红球等刺激,指导家长在家中进行视听、感知觉及运动方面的干预训练,并于生后2周口服小施尔康滴剂1.0ml/d共8周。对所有儿童每月进行随访,小儿1岁时用婴幼儿智能发育量表Gesell(中国标准化)测定其发育商(Development Quotient DQ)。结果:智能测试综合指标:早产治疗组与早产对照组相比具非常显著性差异(F=9.28,P=0.00);早产治疗组与足月对照组相比无显著性差异(F=0.56,P=0.70);早产对照组与足月对照组相比具非常显著性差异(F=9.96,P=0.00)。维生素加早期干预组在运动能、应物能、言语能、应人能等能区与早产对照组相比,有显著性差异,与正常出生体重儿相比无差异。结论:维生素加早期干预对早产低出生体重儿在婴儿期智能发育方面有良好的促进作用。

Vitamins and early interference improves preterm low birth weight infant's intelligence development.

Objective:To explore the influence of the vitamins and early interference to preterm low birth weight infant's intelligence development.Methods:160 prematures born at the eighth hospital of Qingdao were randomly divided into vitamins and interference group and comparison group.80 normal birth weight infants were collected as normal comparison group.The babies in the Vitamins and interference group got tactile impression,listened to background music and saw red balls.Parents gave them interference training at home including seeing,listening,sense impressions movements.2 weeks later Xiaoshierkang 1.0 ml/d PO 8 weeks.All the babies were followed-up every month.The DQ of the babies in three groups were monitored with the method of Gesell Baby Development Test when the babies were 12-months old.Results:Compared with the intelligence development of the general areas,there were significant difference between group 1 and group 2(F=9.28,P=0.00).There were no difference between group 1 and group 3(F=0.56,P=0.70).There were significant difference between group 2 and group 3(F=9.96,P=0.00).The development quotients(DQ)of the preterm low birth weight infants who given Vitamins and early interference in motor,adaptive,language and personal/social areas were significantly higher than the premature babies and no difference from the normal birth weight babies.Conclusion:Vitamins and early interference to the preterm low birth weight can improve babies'intelligence development.