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乳腺癌影像学诊断方法的ROC评价
引用本文:倪俊,顾海峰,张杏梅,陈瑞彩.乳腺癌影像学诊断方法的ROC评价[J].中华全科医学,2012,10(5):790+796.
作者姓名:倪俊  顾海峰  张杏梅  陈瑞彩
作者单位:中国人民解放军第八五医院烧伤整形及乳腺外科
摘    要:目的用受试者工作特性曲线评价超声检查和乳腺X线摄影术诊断乳腺癌的价值。方法选取手术前行超声检查和乳腺X线摄影术检查的88例乳腺疾病患者(其中乳腺癌病患者38例,乳腺良性疾病患者50例)。对超声检查和乳腺X线摄影术的影像学资料进行分析,以手术病理诊断为金标准,分为肯定良性、可能良性、不确定、可能恶性、肯定恶性5个诊断等级。采用SPSS 13.0软件建立受试者工作特性曲线,计算曲线下面积。结果超声检查和乳腺X线摄影术诊断乳腺癌的曲线下面积分别为0.828(SE=0.045)和0.811(SE=0.053),两者之间差异无统计学意义(Z=0.245,P>0.05)。结论超声检查和乳腺X线摄影术对乳腺癌的诊断准确性中等,两者差异无统计学意义。在基层医院进行乳腺癌影像学检查时,可首选无创、简便、经济、有效的超声检查。

关 键 词:乳腺肿瘤  超声检查  乳房X线摄影术  受试者工作特性曲线

Value of Ultrasonography and Mammography in Diagnosis of Breast Cancer by Receiver Operation Characteristic Curve
Affiliation:NI Jun,GU Hai-feng,ZHANG Xing-mei,et al.Department of Burns,Plastic and Breast Surgery,85th Hospital,PLA,Shanghai 200052,China
Abstract:Objective To evaluate the value of ultrasonography and mammography in diagnosis of breast cancer using receiver operation characteristic(ROC) curve analysis.Methods 88 patients with breast disease(38 malignant and 50 benign) were performed ultrasonography and mammography before operation.The results of two diagnosis methods were compared with those of pathology diagnosis.The diagnostic performance was evaluated by ROC curve analysis that was made with SPSS 13.0 and the values of area under the curve(AUC) were calculated.Results AUC of ultrasonography and mammography were 0.828(SE=0.045) and 0.811(SE=0.053) respectively.There were no significant differences between two diagnosis methods(Z=0.245,P>0.05).Conclusion Ultrasonography and mammography were effective methods in the diagnosis of breast cancer.Ultrasonography can be regarded as a non-invasive,simple,economic and effective method for breast cancer in primary hospital.
Keywords:Breast cancer  Ultrasonography  Mammography  Receiver operation characteristic curve
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