| Ⅵ型分泌系统研究进展 |
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| 引用本文： | 魏丹丹,谢中艺,杨帆帆,尹芬芬,黄新祥,张盈.Ⅵ型分泌系统研究进展[J].中国人兽共患病杂志,2020,36(7):599-604. |
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| 作者姓名： | 魏丹丹 谢中艺 杨帆帆 尹芬芬 黄新祥 张盈 |
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| 作者单位： | 江苏大学医学院,镇江 212013 |
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| 基金项目： | 中国博士后科学基金资助项目(No.2018M642186) |
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| 摘 要： | VI型分泌系统(Type VI secretion system,T6SS)是存在于约25%革兰阴性细菌中的一种分泌系统。研究表明T6SS不仅具有对抗其他细菌和杀伤真核宿主细胞的能力,还与细菌的生存及致病能力等方面有着密切的联系。T6SS在不同菌种中表达与功能差异较大,多种致病菌T6SS得到了广泛的研究及讨论。本文主要对T6SS的结构、表达及其功能进行综述,为后续相关研究提供思路。
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| 关 键 词： | VI型分泌系统 生物膜 抗菌作用 致病能力 |
| 收稿时间： | 2019-12-31 |
Progress in research on Type VI secretion system |
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| WEI Dan-dan,XIE Zhong-yi,YANG Fan-fan,YIN Fen-fen,HUANG Xin-xiang,ZHANG Ying.Progress in research on Type VI secretion system[J].Chinese Journal of Zoonoses,2020,36(7):599-604. |
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| Authors: | WEI Dan-dan XIE Zhong-yi YANG Fan-fan YIN Fen-fen HUANG Xin-xiang ZHANG Ying |
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| Affiliation: | School of Medicine, Jiangsu University, Zhenjiang 212013, China |
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| Abstract: | Type VI secretion system (T6SS) is a secretory system that exists in about 25% of Gram-negative bacteria. Studies have shown that the T6SS not only has the ability to fight other bacteria and kill eukaryotic host cells, but also has a close relationship with the survival and pathogenic ability of bacteria. The expression and function of the T6SS in different strains are quite different. T6SS of various pathogenic bacteria have been extensively studied and discussed. This article mainly reviews the structure, expression and function of T6SS to provide ideas for subsequent related research. |
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| Keywords: | Type VI secretion system biofilm antibacterial effect pathogenic ability |
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