126例晚期胃癌患者中医证素特点研究

目的：探讨晚期胃癌患者的中医证素特点，初步揭示晚期胃癌的中医病理特性。方法采用中医证素辨证方法，观察126例晚期胃癌患者的症状、体征，分析各个证素的频数分布及证素积分。结果晚期胃癌的病位证素主要为：胃、脾、肝、肾、胆、肺、大肠、小肠、胞宫、心、脑(神)、膀胱，其中胃、脾、肝和肾所占比例均＞50%。晚期胃癌患者病位证素积分中，脾与胃证素积分比较，差异无统计学意义(P＝0.076)；肝、肾、肺、胆、大肠、小肠证素与脾(t值依次为5.053、4.815、4.465、3.938、4.730、4.278)、胃(t值依次为7.126、6.699、5.679、5.484、6.255、5.604)证素比较，差异有统计学意义(P值均＜0.05)；病性证素主要为：气虚、血虚、气滞、血瘀、邪毒、痰、湿、阴虚、气逆、热、食积、水停、阳虚，其中气滞、血瘀、邪毒、痰、湿、阴虚、气逆、热、食积、水停、阳虚病性证素与气虚(t值依次为3.338、4.664、5.998、6.046、6.024、6.116、6.225、5.889、5.727、5.767、4.718)、血虚(t值依次为2.021、3.402、4.540、4.625、4.688、4.892、5.025、4.843、4.738、4.792、3.936)病性证素比较，差异有统计学意义(P值均＜0.05)。结论晚期胃癌中医病位证素主要集中在脾、胃、肝和肾，病性证素主要有气虚、血虚，但气滞、血瘀、邪毒、痰、湿、阴虚、气逆、热、食积、水停、阳虚也是不可忽视的病性证素。

Clinical study on the characteristics of the TCM syndromes s of the patients with advanced gastric cancer

Objective The purpose is to discuss the characteristics of the TCM syndromes of the patients with advanced gastric cancer, in order to reveal the pathological characteristics of Chinese medicine. Methods By observing the symptoms and signs of 126 patients with advanced gastric cancer, the TCM syndromes was used to analyze the distribution of TCM syndromes' frequency and the scores of symptoms. Results The resut showed that the common TCM syndromes for the disease location were stomach, spleen, liver, kidney, gallbladder, large intestine, small intestine, lung, utreus, heart, brain and bladder, where the frequency of stomach, spleen were higher than other. And the common TCM syndromes for the disease pathology were Qi deficiency, blood deficiency, Qi stagnation, blood stasis, toxin, phlegm, dampness, Yin deficiency, Qi revresion, heat, food stagnation, water stagnation and Yang deficiency.Conclusions The common TCM syndromes for the disease location of advanced gastric cancer were stomach, spleen, liver, kidney; And the common TCM syndromesfor the disease pathology were Qi deficiency and blood deficiency, Qi stagnation, blood stasis, toxin, phlegm, dampness, Yin deficiency, Qi revresion, heat, food stagnation, water stagnation and Yang deficiency.