Biomi metic coating of calciumphosphate on biometallic materials

1 INTRODUCTIONIn the recent years ,there is a huge develop-ment in biomaterials that are specially designed torepair and reconstruct damaged or diseased parts ofthe human bones1 5]. Biometallic materials , suchas titaniumand titaniumalloys , have been mainlyused as bonei mplants due totheir good biocompat-ibility . However , a fibrous tissue was normallydetected at the interface between bone and bio-material due to its poor osteoconductivity , whichfinally would result in the lossening of…

Biomimetic coating of calcium phosphate on biometallic materials

The biomimetic coating process in comparison with other processes is reviewed. This processing shows advantages in the surface bio-modification, such as low cost and flexible processing, wide range of apatite composition and thickness, non-line-of-sight characteristic and possibility to coat polymers and porous implants. The bio-mimetic apatite coating is made up of larger number of globules with size of 1-5μm. Each globule is a group of numerous flakes with a size range of 100-200nm to 30μm in length and 0.1-1μm in thickness. In-vitro and in-vivo studies show that the biomimetic apatite coating can promote an early and strong bonding to bone or promote the bone in-growth into the porous structure, which will be beneficial to the cementless stable fixation of orthopaedic implants. Recently developed co-precipitation of a kind of protein molecules into the HA coating shows much promising.