顽固性心力衰竭患者应用多巴胺与美托洛尔的疗效及预后 |
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引用本文: | 汪爱民.顽固性心力衰竭患者应用多巴胺与美托洛尔的疗效及预后[J].中国循证心血管医学杂志,2011,3(5):371-373. |
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作者姓名: | 汪爱民 |
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作者单位: | 四川省自贡市荣县人民医院心内科,643100 |
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摘 要: | 目的探讨顽固性心力衰竭患者应用多巴胺与美托洛尔联合治疗的临床疗效及预后。方法回顾性分析76例在我院住院NYHA心功能Ⅲ-Ⅳ级难治性心力衰竭患者。按治疗方案不同分为两组:对照组37例,给予常规抗心力衰竭药物治疗;研究组39例,在常规抗心力衰竭药物治疗基础上给予多巴胺与美托洛尔联合治疗。疗程为1个月,治疗前后两组患者分别进行6min步行试验和心脏超声检查,对比两组患者心功能改变。随访1年后,比较两组患者再入院及猝死发生率。结果与对照组相比,研究组在6min步行试验距离、心率、左室射血分数、左室舒张末期内径及每搏输出量上有明显改善(P〈0.05);研究组再入院率、猝死率均低于对照组(P〈0.05)。结论多巴胺与美托洛尔联合治疗难治性心力衰竭临床疗效明显,预后显著改善。
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关 键 词: | 顽固性心力衰竭 多巴胺 美托洛尔 临床疗效 预后 |
Curative effect of dopamine and metoprolol and prognosis in patients with intractable heart failure |
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Authors: | WANG Ai-min |
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Affiliation: | WANG Ai-min.Department of Cardiology,Rong County People's Hospital,Zigong City,Sichuan Province,Zigong 643100,China. |
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Abstract: | Objective To probe into the clinical curative effect of dopamine and metoprolol and prognosis in patients with intractable heart failure.Methods The patients with intractable heart failure(NYHA heart function III-IV grades,n=76) were retrospectively analyzed and they were divided into two groups according to the therapeutic plans:the control group(n=37) treated with routine anti-heart failure medications,and research group(n=39) treated with dopamine and metoprolol on the base of routine anti-heart failure ... |
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Keywords: | Intractable heart failure Dopamine Metoprolol Clinical curative effect Prognosis |
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