| 贞芪扶正胶囊对免疫力低下小鼠免疫功能的影响研究 |
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| 引用本文： | 李红,;任远,;吴国泰.贞芪扶正胶囊对免疫力低下小鼠免疫功能的影响研究[J].中国药房,2009(24):1853-1854. |
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| 作者姓名： | 李红 ;任远 ;吴国泰 |
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| 作者单位： | [1]甘肃天水市第四人民医院,天水市741000; [2]甘肃中医学院,兰州市730000 |
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| 摘 要： | 目的:研究贞芪扶正胶囊(ZQFZ)对免疫力低下小鼠免疫功能的影响。方法:用环磷酰胺复制小鼠免疫功能低下模型,通过测定腹腔巨噬细胞吞噬功能、迟发型超敏反应和溶血素抗体等指标,观察ZQFZ对小鼠非特异性免疫、细胞免疫和体液免疫功能的影响。结果:ZQFZ可显著促进小鼠腹腔巨噬细胞吞噬功能,提高吞噬率和吞噬指数;显著增强二硝基氯苯所致迟发型超敏反应;提高血清溶血素抗体水平。结论:ZQFZ对免疫力低下小鼠免疫功能有显著促进作用。
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| 关 键 词： | 贞芪扶正胶囊 免疫功能 实验研究 |
Effect of Zhenqi Fuzheng Capsules on the Immune Function of Hypoimmune Mice |
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| Affiliation: | LI Hong, REN Yuan,WU Guo-tai(Gansu Tianshui Forth People＇s Hospital, Tianshui 741000, China;Gansu College of Traditional Chinese Medicine, Lanzhou 7a0000, China) |
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| Abstract: | OBJECTIVE： To study the effect of Zhenqi fuzheng capsules（ZQFZ） on the immune function of hypoimmune mice. METHODS： The hypoimmune mice model was established using cyclophosphamid ; the effects of ZQFZ on the nonspecific immunity, cell immunity and humoral immune function of mice were observed by determining the function of peritoneal maerophage, the delayed hypersensitivity and serum antibody of hemolysin etc. RESULTS： ZQFZ significantly promoted the function of peritoneal macrophages, improved the phagocytic rate and phagocytic index, markedly enhanced the dinitro- chlorobenzene - induced delayed hypersensitivity, and upregulated the serum antibody level of hemolysin. CONCLUSION： ZQFZ have remarkable action in promoting the immune function of hypoimmune mice. |
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| Keywords: | Zhenqi fuzheng capsule Immune function Experimental study |
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