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我院451例药品不良反应报告分析
引用本文:庄权权.我院451例药品不良反应报告分析[J].中国执业药师,2011,8(5):7-9,12.
作者姓名:庄权权
作者单位:福建省泉州市第一医院药剂科,福建,泉州,362000
摘    要:目的:了解我院药品不良反应(ADR)发生情况及相关因素,为合理用药提供参考。方法:对我院2010年收集的451例ADR报告进行统计、分析。结果:451例ADR报告共涉及16类药品,静脉滴注是引起ADR的主要给药途径(85.18%);抗感染药物发生率最高(33.26%),其次是消化系统药(14.41%)、营养药(9.98%)、影响血液和造血系统的药物(7.32%);临床表现主要为消化系统损害(25.06%)。结论:ADR的发生与多种因素有关,临床应加强ADR监测工作,以减少或避免ADR的发生。

关 键 词:药品不良反应  报告  合理用药

A Report on the Analysis of 451 Cases of Adverse Drug Reactions in Our Hospital
Authors:Zhuang Quanquan
Affiliation:Zhuang Quanquan( Pharmacy Department of the First Hospital of Quanzhou,Fujian Quanzhou 362000,China)
Abstract:Objective:To study the situation and the related factors of ADR occurred in our hospital and to provide references for rational use of drugs. Methods:A total of 451 case reports collected in our hospital in 2010 were analyzed statistically. Results:Of the 451 ADR cases,16 kinds of drugs were involved. About 85.18% of ADRs were induced by intravenous drip infusion,and the ADRs caused by antibacterials,drugs for digestive system, nutritious drugs and the drugs for circulation and hematopoietic system were 33.26% ,14.41%,9.98% and 7.32% respectively. The main clinical manifestations represented as lesion of gastrectasis system (25.06%). Conclusion: ADRs may be caused by various factors. ADR monitoring in clinic should be strengthened so as to reduce or avoid occurrence of ADR.
Keywords:Adverse Drug Reaction(ADR)  Report Forms  Rational Use of Drugs
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