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轻度认知损害中医证候与1H-MRS功能改变的关系
引用本文:张立苹,张红,时晶,苗迎春,谭中建.轻度认知损害中医证候与1H-MRS功能改变的关系[J].北京中医药大学学报,2011,34(5):353-357,360.
作者姓名:张立苹  张红  时晶  苗迎春  谭中建
作者单位:北京中医药大学东直门医院放射科,北京,100700;北京中医药大学东直门医院老年病科
基金项目:北京中医药大学自主选题项目
摘    要:目的 基于核磁共振代谢组学分析方法,探讨遗忘型轻度认知损害(amnestic mild cognitive impairment,aMCI)主要证型(肾虚证和痰浊证)的1H-MRS代谢物比值与认知功能的相关特征.方法 采用德国Siemens公司生产的Novus 1.5T磁共振成像系统,对入选的研究对象行相应的常规MRI...

关 键 词:轻度认知损害  简易精神状态检查  磁共振波谱  中医证候

Relationship between TCM syndromes and changes of 1H-MRS of mild cognitive impairment
ZHANG Li-ping,ZHANG Hong,SHI Jing,MIAO Ying-chun,TAN Zhong-jian.Relationship between TCM syndromes and changes of 1H-MRS of mild cognitive impairment[J].Journal of Beijing University of Traditional Chinese Medicine,2011,34(5):353-357,360.
Authors:ZHANG Li-ping  ZHANG Hong  SHI Jing  MIAO Ying-chun  TAN Zhong-jian
Affiliation:ZHANG Li-ping1,ZHANG Hong1,SHI Jing2,MIAO Ying-chun2,TAN Zhong-jian1(1 Department of Radiology,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,2 Department of Geratology,Beijing University of Chinese Medicine)
Abstract:Objective To investigate the related characteristics of the ratio of metabolites of 1H-magnetic resonance spectroscopy(1H-MRS) and cognitive function in amnestic mild cognitive impairment(aMCI) of kidney deficiency type or phlegm turbidity type based on the analysis of nuclear magnetic resonance metabonomics.Methods The subjects were given routine magnetic resonance imaging(MRI) for collecting 1H-MRS data in brain region of interest.In 38 patients with aMCI(17 in kidney-deficiency group and 21 of phlegm-tur...
Keywords:mild cognitive impairment  MMSE  magnetic resonance spectrum  TCM syndromes  
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