视空间认知与脑血流速度的相关性研究

目的:探讨视觉空间认知活动对脑血流速度(CBFV)的影响及性别和任务完成质量对相对的CBFV变化的影响。方法:在完成视觉空间认知活动时及其先前的休息期,对45个正常的志愿者(右利手)用经颅超声多普勒(TCD)监测其双侧大脑中动脉血流速度的变化。结果:完成认知任务时与休息时期相比,所有认知任务的完成均诱导出双侧大脑中动脉血流速度的显著变化(P<0.001),这种变化显示出显著的右侧大脑半球偏侧化(P<0.01)。性别对认知活动所诱导的脑血流速度未产生显著的影响(P >0.05),任务表现质量(得分)对CBFV的变化不产生显著的影响。结论:视觉空间认知活动可诱导CBFV的右侧偏侧化。

A Study of the Correlation between Visual Spatial Cognitive Activities and Cerebral Blood Flow Velocity Changes in Normal Young People

Objective: We sought to investigate the effect of CBFV induced by visual spatial Cognitive Activities and to determine the influence of gender, quality of the performance on the relative CBFV changes. Methods: Simultaneous bilateral TCD monitoring of CBFV in the middle cerebral arteries (MCAs) was performed in 45 right-handed normal volunteers during 11 verbal and visuospatial tasks and their preceding rest periods. Results: All tasks induced a significant bilateral CBFV increase in the MCAs compared with the preceding rest periods and showed a significant lateralized right-hemispheric acceleration(P<0.01). Gender did not show higher relative CBFV changes(P>0.05). Performance quality did not reveal significant effects on CBFV change. Conclusion: Visual spatial cognitive activities can induce a significant lateralized right-hemispheric acceleration.