| 氯丙嗪抗实验性心律失常的初步观察 |
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| 引用本文： | 于肯明,白建平,李月英,王树华,张俊霞.氯丙嗪抗实验性心律失常的初步观察[J].大同医学专科学校学报,1997(2). |
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| 作者姓名： | 于肯明 白建平 李月英 王树华 张俊霞 |
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| 作者单位： | 大同医专教务处
(于肯明)，大同医专药理教研室
(白建平，李月英，王树华)，大同第一制药厂医务科(张俊霞) |
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| 摘 要： | 本文观察了氯丙嗪抗实验性心律失常作用。结果显示,氯丙嗪能降低氟仿诱发小鼠室颤率;可对抗Bacl2所致大鼠室性心律失常;可明显提高乌头碱诱发大鼠心律失常用量;可防治肾上腺素诱发家兔产生的心律失常。 大同医专教务处副处长,037008 大同医专药理教研室 大同第一制药厂医务科
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| 关 键 词： | 氯丙嗪 实验性心律失常 |
Antiarrhythmic experimental observation of chlorpromazine |
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| Yu kenming. Be Jindin,Li Yueging,et at.Antiarrhythmic experimental observation of chlorpromazine[J].Journal of Datong Medical College,1997(2). |
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| Authors: | Yu kenming Be Jindin Li Yueging et at |
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| Affiliation: | Dept ment of pharmacology Datong Medicalccllege |
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| Abstract: | chlorpromazine has many pharmacologi cal effects,but the antiarrhythmic effects have never been reported. Th is article reports antiarrhythmic effeccs of chlorprmoaline in animal experiment. Result shows that chlorpromazine can reduce the incidence of ventricular fibrillation caused by chloroforne in mice (P<0. 01)lower incidence of arrhythmica induced by adrenaline in rabbits (P<0. 05),Shorten arrhythmic sustained time induced by Ba-cl2(P<0. 01) .Postpone occurrence of arrhythmic induced by increacing the dose of aconitine (P<0. 01). It's thus clear that chlo.rpromazine have abvious antiarrhythmic effects, The maehanism of antiarrnythmia remains to be reserched farther. |
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| Keywords: | chlorpromazim experimental arrhythmia |
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