自噬细胞在肾脏移植中的研究进展

在受到缺血、毒性或免疫性损伤后，肾脏细胞必须适应其周围环境并维持必要的代谢，才能避免细胞死亡。在这个适应过程中，自噬可以综合协调胞内和细胞外的众多触发机制（营养或者免疫刺激），从而调节细胞活力、先天性和获得性免疫功能。本综述整理最近在肾脏移植领域发表的与自噬相关文献，以探讨未来的研究方向。

Advances in research of autophagic cells in kidney transplantation

After being subject to ischemic, toxic or immunological damage, kidney cells must adapt to their surroundings and maintain the necessary metabolism to avoid cell death. In this adaptation process, autophagy can coordinate multiple intracellular and extracellular triggering mechanisms (nutritive or immune stimulation) to regulate cell viability, innate and acquired immune function. The purpose of this paper is to review recent literature on autophagy published in the field of kidney transplantation to explore future research directions.