| 胃癌组织溶菌酶、α_1抗胰蛋白酶及α_1抗凝乳蛋白酶的免疫组化研究 |
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| 引用本文： | 许群,杜卫东.胃癌组织溶菌酶、α_1抗胰蛋白酶及α_1抗凝乳蛋白酶的免疫组化研究[J].肿瘤防治研究,1995,22(4):199-201. |
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| 作者姓名： | 许群 杜卫东 |
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| 作者单位： | 1. 徐州市医学科学研究所;
2. 徐州医学院病理学教研室 |
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| 摘 要： | 本文对４５例胃癌手术标本进行了ＬＺＭ、ＡＡＴ及ＡＣＴ的免疫组化定位观察。结果发现胃癌细胞具有一定合成ＬＺＭ、ＡＡＴ及ＡＣＴ的能力，ＬＺＭ阳性率的高低与胃癌的分化程度及淋巴结转移密切相关（Ｐ＜０．０５），分化程度较好，粘液分泌亢进以及临床呈良性经过的胃癌ＬＺＭ、ＡＡＴ及ＡＣＴ阳性率有增高的趋势。提示ＬＺＭ、ＡＡＴ及ＡＣＴ可用于临床判断恶性度，估价预后的潜在价值。
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| 关 键 词： | 胃肿瘤 溶菌酶 AAT ACT 免疫组织化学 |
Immunohistochemical Studies of Lysozyme，α1Antitrypsin，and α1Antichymotrypsin in Gastric Carcinoma Tissues |
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| Xu Qun.Immunohistochemical Studies of Lysozyme，α1Antitrypsin，and α1Antichymotrypsin in Gastric Carcinoma Tissues[J].Cancer Research on Prevention and Treatment,1995,22(4):199-201. |
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| Authors: | Xu Qun |
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| Affiliation: | Xuxhou Institute of Medical Sciences |
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| Abstract: | Abstract The gastric tissues were taken from 45 patients with carcinoma of stomach during operation to study the immunohistochemical localization of LZM, AATand ACT. It was found that the cancer cells could synthesize LZM,AAT and ACT to some extent. The detected amount of LZM had a positive correlation with the degree of differentiation and metastasis rate of lymph gland (P0. 05). In gastric carcinoma with more complete differentiation, a strong secretion of mucus and a benigh clinical course, LZM, AAT, and ACT tended to enhance. These results suggest that LZM, AAT, and ACT may have a potential value in estimation of malignant degree and prediction of prognosis. |
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