蛇毒清合剂治疗海蛇咬伤临床观察

目的观察蛇毒清合剂对海蛇咬伤的疗效。方法将44例海蛇咬伤患者分为治疗组22例，对照组22例，两组患者均给予常规治疗，治疗组加服蛇毒清合剂，并比较两组患者咬伤48h后的血清酶学三项（CK、LDH、AST），比较两组患者治疗7天后的疗效、治疗结束时疗程及呼吸衰竭发生率、急性肾损伤发生率。结果两组患者临床疗效比较，治疗组优于对照组（P〈0．05），酶学三项和疗程的差异均有统计学意义（P〈O．05）}其呼吸衰竭发生率、急性肾损伤发生率虽有差异，但无统计学意义（P〉0．05）。结论蛇毒清合剂对海蛇咬伤有显著疗效。

Observation of Clinic efficacy of Sheduqing mixture on treatment of Bites by Sea Snakes

Objective To observe the clinic efficacy of Sheduqing mixture on treatment of bites by Sea Snakes.Methods 44 cases of bites by Sea Snakes was divided into two groups: the treatment group(22 cases) and the control group(22 cases).All of them were accepted regular treatment.The treatment group were treated with Sheduqing mixture in addition.To compare the data of serum CK,LDH,AST between two groups(after 48 h),to compare the therapeutic efficacy(after 7 days),the period of treatment,the number of respiratory failure and the number of acute kidney injury(AKI) between two groups.Results The clinical efficacy between two groups had significant difference(P<0.05);the serum CK,LDH,AST of two groups,the period of treatment between two groups had significant difference(P<0.05);the number of respiratory failure and the number of AKI between two groups had difference,but the difference had no statistical significance(P>0.05).Conclusion Sheduqing mixture had marked efficacy in treatment of bites by Sea Snakes.