Abstract: | N-(9-Fluorenylmethoxycarbonyl)-ω-aminoalkyl-, N-(9-fluorenylmethoxycarbonyl)-8-amino-3,6-dioxaoctyl, and N-(9-fluorenylmethoxycarbonyl)-6-aminohexanoyl]-2-aminoethyl triphosphates were synthesized. All of them were shown to be the substrates of the calf thymus terminal deoxynucleotidyl transferase. Their substrate properties depend on the length and structure of the linker between the 9-fluorenylmethoxycarbonyl and triphosphate moieties.__________Translated from Bioorganicheskaya Khimiya, Vol. 31, No. 4, 2005, pp. 394–398.Original Russian Text Copyright © 2005 by Khandazhinskaya, Kukhanova, Jasko. |